Results 81 to 90 of about 174,092 (264)
Modulation of host immunity by Treg-inducing Bacteria
, 2019 Intestinal microbiota plays a critical role in the modulation of human health. Dysregulation of the commensal flora is closely linked to functional changes of the immune system and subsequently contributes to development of immune disorders.
IM, SIN HYEOG
core
Suppressive capacity of Treg cells treated with dendrimers.
, 2016 Mean + SEM of the percentage of CD69 and CD154 activation markers in stimulated allogeneic PBMC alone (PBM ST) and co-cultured with Treg cells treated or non-treated (Treg NT) with cationic or anionic dendrimers (Treg: PBMC ratio of 1:1). Treg NT (n = 5),
Didiana Jaramillo-Ruiz (846629) +4 more
core +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Alteration of Treg compartments in HIV+ and healthy individuals.
, 2019 (A) Frequencies and (B) absolute numbers (AbsN) of Treg, activated Treg (Treg Act+: CD25+CD127negHLA-DR+CD45RO+) and Treg TemRA (CD25+CD127negCD27negCD45RA+) were determined in whole blood using cell surface labeling.
Verónica Pérez-Fernández (6519359) +7 more
core +1 more source
Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation [PDF]
, 2008 BACKGROUND: Treg based immunotherapy is of great interest to facilitate tolerance in autoimmunity and transplantation. For clinical trials, it is essential to have a clinical grade Treg isolation protocol in accordance with Good Manufacturing Practice ...
Irma Joosten +17 more
core +2 more sources
Advanced Science, EarlyView.A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu +4 more
wiley +1 more source
, 2011 The acute phase protein serum amyloid A (SAA) has been well characterized as an indicator of inflammation. Nevertheless, its functions in pro versus anti-inflammatory processes remain obscure.
Jane L. Park +7 more
core +1 more source
Advanced Science, EarlyView.DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu +6 more
wiley +1 more source
Инфекция и иммунитет, 2018 On the background of a high level of genetic susceptibility to tuberculosis infection (TB), granulomatous reactions in the lung tissue fail to effectively isolate infection foci and rather result in diffuse pathology, confluence of granulomata and ...
E. I. Rubakova +4 more
doaj +1 more source
Advanced Science, EarlyView.Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng +13 more
wiley +1 more source