Results 101 to 110 of about 156,448 (312)

Peripheral Blood from Rheumatoid Arthritis Patients Shows Decreased Treg CD25 Expression and Reduced Frequency of Effector Treg Subpopulation

, 2021
Rheumatoid arthritis (RA) is a common autoimmune disease characterized by immune cell infiltration of the synovium, leading to the loss of cartilage, bone, and joint function.
Ju-Gyeong Kang, Bu Yeon Heo, Eunbyeol Go, Heo, Bu Yeon, Somin Kwon, Sun, Pureum, Kwon, Somin, Suyoung Choi, Yeeun Kim, Shin, Eui-Cheol, Jinhyun Kim, Jaeyul Kwon, Kwon, Jaeyul, Min Kyung Jung, Kim, Jinhyun, Kang, Ju-Gyeong, Eui-Cheol Shin, Pureum Sun, Go, Eunbyeol, Kang, Seong Wook, Choi, Suyoung, Kim, Yeeun, Jung, Min Kyung, Yoo, Su-Jin, Su-Jin Yoo, Seong Wook Kang   +25 more
core   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source

REGULATION OF IMMUNE RESPONSE AGAINST MYCOBACTERIUM TUBERCULOSIS BY THE POPULATION OF REGULATORY DENDRITIC CELLS

Инфекция и иммунитет, 2018
On the background of a high level of genetic susceptibility to tuberculosis infection (TB), granulomatous reactions in the lung  tissue fail to effectively isolate infection foci and rather result in  diffuse pathology, confluence of granulomata and ...
E. I. Rubakova, M. A. Kapina, N. N. Logunova, K. B. Majorov, A. S. Apt   +4 more
doaj   +1 more source

Regulatory T cell proliferative potential as novel marker to investigate immune tolerance and clinical progression in Multiple Sclerosis

, 2011
In autoimmune disorders such as Multiple Sclerosis (MS) one of the determining alteration is the breakdown of self-antigen immune-tolerance. Peripheral immune tolerance is maintained, at least in part, by Regulatory T cells (Treg).
Carbone, Fortunata
core  

T regulatory cells in cord blood--FOXP3 demethylation as reliable quantitative marker [PDF]

, 2010
Regulatory T-cells (Tregs), characterized as CD4+CD25(hi) T-cells expressing FOXP3, play a crucial role in controlling healthy immune development during early immune maturation. Recently, FOXP3 demethylation was suggested to be a novel marker for natural
Laura Layland, Liu, Jing, Jing Liu, Schaub, Bianca, Layland, Laura, Mutius, Erika von, Illi, Sabina, Lluis, Anna, Bianca Schaub, Erika von Mutius, Anna Lluis, Sabina Illi, Olek, Sven, Sven Olek   +13 more
core   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Treg-specific IFNAR deficiency leads to impaired antitumor immune response.

, 2018
(A) IFNARfl/fl and IFNARfl/fl x Foxp3YFP-Cre mice were injected with 2x105 MC38 cells (left panels) and or 1.25x105 B16.F10 cells (right panels) subcutaneously, tumor growth in individual mice (left panels) and in pooled mice (two individual experiments,
Craig Martens (427895), Maria Lopez-Ocasio (5122862), Amina Metidji (5122856), Rachel Baur (5122853), Stephen F. Porcella (42449), Deborah D. Glass (5122859), Eric Dahlstrom (451989), Ethan M. Shevach (3826519), Arunakumar Gangaplara (515129), Ameya S. Gokhale (5122850), Kishore Kanakabandi (553458)   +10 more
core   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Tregs in Immunotherapy: Opportunities and Challenges [PDF]

Immunotherapy, 2011
n ...
openaire   +3 more sources

Analysis of Treg cell population in patients with breast cancer with respect to progesterone receptor status [PDF]

, 2018
Breast cancer is the most frequently diagnosed type of cancer in women worldwide. Both the development and progression of breast cancer are related to tumour evasion of the immune system through a process called cancer immune-editing, in which ...
Dutsch-Wicherek, Magdalena, Maria Szymankiewicz, Magdalena Dutsch-Wicherek, Biedka, Marta, Tomasz Nowikiewicz, Szymankiewicz, Maria, Konrad Dziobek, Marta Biedka, Łukaszewska, Ewelina, Ewelina Łukaszewska, Dziobek, Konrad, Nowikiewicz, Tomasz   +11 more
core   +1 more source