Results 81 to 90 of about 122,409 (259)

The influence of humoral factors of homeostatistic proliferation on t-regulatory cells in vitro

open access: yesБюллетень сибирской медицины, 2019
Aim. The aim of this study was the investigation of the influence of humoral factors of homeostatic proliferation IL-7 and IL-15 on T-regulatory cells in healthy donors.Materials and methods.
D. V. Shevyrev   +2 more
doaj   +1 more source

Chemotherapy‐Mediated Induction of PD‐L1 via SEI1 Facilitates Myeloma Immune Evasion

open access: yesAdvanced Science, EarlyView.
Chemotherapy induces DNA damage, activating cyclic guanosine monophosphate (GMP)‐adenosine monophosphate (AMP) synthase (cGAS)/stimulator of interferon genes (STING), which phosphorylates interferon regulatory factor 7 (IRF7) to drive SERTA‐containing domain 1 (SEI1) transcription.
Rui Chen   +9 more
wiley   +1 more source

Regulatory effect of gut microbes on blood pressure

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 513-531, December 2022., 2022
The interaction between gut microbiota and hypertension, the genera which affect the blood pressure in taxonomic level, and the commonly used treatments to hypertension based on the gut microbes were summarized in this review. The increases of Lactobacillus, etc.
Dong Yan   +6 more
wiley   +1 more source

Convergence, plasticity, and tissue residence of regulatory T cell response via TCR repertoire prism

open access: yeseLife
Suppressive function of regulatory T cells (Treg) is dependent on signaling of their antigen receptors triggered by cognate self, dietary, or microbial peptides presented on MHC II.
Tatyana O Nakonechnaya   +7 more
doaj   +1 more source

The T-Cell Response to Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

open access: yesViruses, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to cause severe reproductive and respiratory pathologies resulting in immense monetary and welfare costs for the swine industry.
Andrew R. Kick   +6 more
doaj   +1 more source

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

open access: yesAdvanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen   +16 more
wiley   +1 more source

The protective effects of Xuebijing injection on intestinal injuries of mice exposed to irradiation

open access: yesAnimal Models and Experimental Medicine, Volume 5, Issue 6, Page 565-574, December 2022., 2022
Xuebijing injections (XBJ) is a traditional Chinese medicine (TCM), approved for the sepsis treatment of by the China Food and Drug Administration. XBJ can effectively enhance the mice survival rate after total body irradiation (TBI). XBJ protects the crypt‐villus structure, maintains the proliferation and differentiation of the small intestine after ...
Yinping Dong   +9 more
wiley   +1 more source

Integrated analysis of single-cell and bulk RNA sequencing data reveals a cellular senescence-related signature in hepatocellular carcinoma

open access: yesFrontiers in Cell and Developmental Biology
The mortality of hepatocellular carcinoma (HCC) is on the rise globally, particularly in the Western world, with etiology gradually shifting from virus-related liver diseases to metabolic disorders such as non-alcoholic fatty liver disease.
Lei Qiao   +10 more
doaj   +1 more source

The Effect of Schisandrin B on the Development of Multiple Sclerosis

open access: yesProceedings, 2019
Multiple Sclerosis (MS) is a chronic inflammatory, demyelinating neurodegenerative disease targeting the central nervous system. The pathogenesis of MS is a process of innate and adaptive immune system components.
Mustafa Cakir   +3 more
doaj   +1 more source

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