Results 61 to 70 of about 49,489 (310)

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Supramolecular Gels as Active Tools for Reaction Engineering

open access: yesAngewandte Chemie, EarlyView.
The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley   +2 more sources

Pseudo-Four Component Synthesis of Mono- and Di-Benzylated-1,2,3-Triazoles Derived from Aniline

open access: yesMolecules, 2013
The pseudo-four component click synthesis of dibenzylated 1,2,3-triazoles derived from aniline is reported. The cycloaddition of sodium azide to N-(prop-2-ynyl)-benzenamine (I) in the presence of equimolar amounts of p-substituted benzyl derivatives ...
Daniel Mendoza-Espinosa   +4 more
doaj   +1 more source

Synthesis and biological evaluation of quinoline-triazole and quinolone-triazole conjugates

open access: yesTURKISH JOURNAL OF CHEMISTRY, 2018
One-pot synthesis of novel quinoline- and quinolone-substituted 1,2,3-triazoles has been performed from the key intermediates, quinoline- and quinolone-substituted propargyl derivatives 1-3 (48%-88% yields). The antioxidant properties of the newly synthesized compounds, 1a-1c, 2a-2c , and 3a-3c , were evaluated by monitoring DPPH (2,2-diphenyl-1 ...
Ayşegül GÜMÜŞ, Veysi OKUMUŞ
openaire   +3 more sources

Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]

open access: yes, 2015
The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy   +3 more
core   +2 more sources

Supramolecular Chemistry in Metal–Organic Framework Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ   +3 more
wiley   +1 more source

Adsorption and Separation by Flexible MOFs

open access: yesAdvanced Materials, EarlyView.
Flexible metal–organic frameworks (MOFs) present significant potential for gas storage and separation due to their structural dynamic. This review explores the rationale behind the flexible MOFs' enhanced working capacity and separation factors. It also addresses key challenges, including phase transition kinetics, crystal robustness, cycling, shaping,
Irena Senkovska   +4 more
wiley   +1 more source

Enantioconvergent Deacylative Functionalization toward α‐Quaternary Nitriles

open access: yesAngewandte Chemie, EarlyView.
An enantioconvergent quaternary‐to‐quaternary synthesis of α‐chiral nitriles has been enabled. By replacing the acyl group with a variety of allyl, propargyl, and benzyl motifs, the functional group swap can convert easily available β‐ketonitriles to assorted quaternary stereocenters en route to bioactive molecules of broad interests.
Minghao Zhang, Zhongxing Huang
wiley   +2 more sources

Sensibilidad in vitro a benznidazol, nifurtimox y posaconazol de cepas de Trypanosoma cruzi de Paraguay

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2020
Introducción. Trypanosoma cruzi, agente causal de la enfermedad de Chagas, exhibe una sustancial heterogeneidad fenotípica y genotípica que puede influir en las variaciones epidemiológicas y clínicas de la enfermedad, así como en la sensibilidad a los ...
Nidia Acosta   +6 more
doaj   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

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