Results 61 to 70 of about 75,158 (330)
Recent Advancements in Triazole-based Click Chemistry in Cancer Drug Discovery and Development
SynOpen, 2023 Triazole-based compounds possess a broad range of activity and can be synthesized using click chemistry. Many new chemotherapeutic agents have been developed in recent years by exploiting click chemistry and these are covered in this review.
Arun Kumar +3 more
doaj +1 more source
Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates [PDF]
, 2014 The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine ...
Harris, Robert +2 more
core +1 more source
Deoxygenative C2-heteroarylation of quinoline N-oxides: facile access to α-triazolylquinolines
Beilstein Journal of Organic Chemistry, 2021 A metal- and additive-free, highly efficient, step-economical deoxygenative C2-heteroarylation of quinolines and isoquinolines was achieved from readily available N-oxides and N-sulfonyl-1,2,3-triazoles. A variety of α-triazolylquinoline derivatives were
Geetanjali S. Sontakke +2 more
doaj +1 more source
Molecules, 2023 A new series of spirooxindoles based on benzimidazole, triazole, and isatin moieties were synthesized via a [3+2] cycloaddition reaction protocol in one step. The single X-ray crystal structure of the intermediate triazole-benzimidazole 4 was solved. The
Saeed Alshahrani +7 more
doaj +1 more source
Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]
, 2016 Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core +3 more sources
Advanced Functional Materials, EarlyView.Poly(heptazine) imides (PHIs), a crystalline carbon nitride subclass, intercalate metals to deliver high stability, tunable electronics, and efficient charge separation. These features enable solar‐driven applications such as hydrogen evolution, CO₂ reduction, and organic synthesis.
Gabriel A. A. Diab +6 more
wiley +1 more source
Theoretical Study of the Addition Reaction of Arylazides to 1,3-Dicarbonyl Compounds
Chemistry Proceedings, 2023 Our research focuses on the synthesis of 1,2,3-triazoles through 1,3-dipolar cycloaddition involving arylazides. The reaction demonstrates high efficiency when conducted in the presence of morpholine, resulting in 100% regioselectivity towards a single ...
Adda Abdelghani +3 more
doaj +1 more source
Computationally motivated synthesis and enzyme kinetic evaluation of N-(β-d-glucopyranosyl)-1,2,4-triazolecarboxamides as glycogen phosphorylase inhibitors [PDF]
, 2015 Following our recent study of N-(β-D-glucopyranosyl)-oxadiazole-carboxamides (Polyák et al., Biorg. Med. Chem. 2013, 21, 5738) revealed as moderate inhibitors of glycogen phosphorylase (GP), in silico docking calculations using Glide have been performed ...
Alex +57 more
core +1 more source
Advanced Functional Materials, EarlyView.Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida +16 more
wiley +1 more source