Results 81 to 90 of about 49,489 (310)

PPh3/Isocyanide and N2/Isocyanide Exchange: Pathways to Isolable Alkali Metal Keteniminyl Anions

open access: yesAngewandte Chemie, EarlyView.
The synthesis of isolable keteniminyl anions through substitution of the phosphine ligand in metalated ylides or the N₂ ligand in diazomethanides with isocyanides is reported. The anions feature a bent geometry, with the angle decreasing with increasing donor ability of the nitrogen substituent, and exhibit broad applicability in the formation of ...
Sunita Mondal   +7 more
wiley   +2 more sources

Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives

open access: yesMolecules, 2021
A new series of mollugin-1,2,3-triazole derivatives were synthesized using a copper(I)-catalyzed Huisgen 1,3-dipolar cycloaddition reaction of corresponding O-propargylated mollugin with aryl azides.
Han Luo   +5 more
doaj   +1 more source

Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]

open access: yes, 2014
Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien   +4 more
core   +1 more source

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li   +10 more
wiley   +1 more source

Self‐Photosensitizing Cobalt Complexes for Photocatalytic CO2 Reduction Coupled with CH3OH Oxidation

open access: yesAngewandte Chemie, EarlyView.
Self‐photosensitizing non‐noble metal complexes achieve CO2 photoreduction coupled with CH3OH photooxidation, simultaneously synthesizing formic acid in the absence of any additional photosensitizers and electron sacrificial reductants. Abstract The use of metal complexes as homogeneous molecular catalysts has attracted considerable attention regarding
Ji‐Hong Zhang   +5 more
wiley   +2 more sources

New Members of the Cinchona Alkaloids Family: Assembly of the Triazole Heterocycle at the 6′ Position

open access: yesMolecules, 2021
The substance class of the well-known Cinchona alkaloids is widened by 6′-Amino-cinchonine and 6′-Amino-cinchonidine, novel compounds which incorporate a primary amino function in the quinolinic ring system.
Catalin Vasile Maftei   +3 more
doaj   +1 more source

Benzotriazole is antiestrogenic in vitro but not in vivo [PDF]

open access: yes, 2007
Copyright © 2007 SETAC. This is the accepted version of the following article: Harris et al (2007), "Benzotriazole is antiestrogenic in vitro but not in vivo", Environmental Toxicology and Chemistry, 26(11), 2367–2372, which has been published in final ...
Brian, JV   +5 more
core   +1 more source

Development of Triazoles and Triazolium Salts Based on AZT and Their Anti-Viral Activity against HIV-1

open access: yesMolecules, 2021
We report herein a set of 3′-azido-3′-deoxythymidine (AZT) derivatives based on triazoles and triazolium salts for HIV-1 infection. The compounds were synthesized via click chemistry with Cu(I) and Ru(II) catalysts.
Daniel Machado de Alencar   +9 more
doaj   +1 more source

Modulare Synthese dendritischer Oligo‐Glycerin‐Kationischer Tenside zur Steigerung der antibakteriellen Wirksamkeit

open access: yesAngewandte Chemie, EarlyView.
Ein orthogonaler Klick‐Chemie‐Ansatz wurde verwendet, um eine Reihe von kationischen Tensiden zu synthetisieren. Die Ergebnisse zeigen, dass ein optimales Gleichgewicht zwischen positiven Ladungen und Hydrophobizität ein entscheidender Faktor für die Verbesserung der antibakteriellen Eigenschaften ist.
Natalie Hanheiser   +8 more
wiley   +1 more source

Antifungal Drugs

open access: yesMetabolites, 2020
We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein ...
Jiří Houšť   +2 more
doaj   +1 more source

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