Results 111 to 120 of about 85,493 (199)

The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration

Orthopaedic Surgery, Volume 18, Issue 9, Page 1804-1818, September 2026.
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou, Jingyi Cai, Weijian Zhu, Sirui Zhou, Liling Zhou, Yiyao Pei, Gang Wu   +6 more
wiley   +1 more source

Functional Specialization of Clathrin‐Independent Endocytic Routes: Mechanisms and Cellular Roles

Traffic, Volume 27, Issue 3, September 2026.
Distinct clathrin‐independent endocytic (CIE) routes support specialized cellular functions across different contexts. Created with Biorender.com. ABSTRACT Clathrin‐independent endocytosis (CIE) comprises a diverse repertoire of internalization mechanisms that operate in parallel with clathrin‐mediated endocytosis.
Andrea Francesco Benvenuto, Amir Fardin, Matteo Balestra, Pier Paolo Di Fiore, Chiara Tordonato, Sara Sigismund   +5 more
wiley   +1 more source

Probing microdomain Ca²⁺ activity and synaptic transmission with a node-based tripartite synapse model. [PDF]

Front Netw Physiol, 2023
Liu L, Gao H, Li J, Chen S.
europepmc   +1 more source

A Possible Role For Astrocytes In Contextual Memory Retrieval: An Analysis Obtained Using A Quantitative Framework

Frontiers in Computational Neuroscience, 2013
The hippocampus is central to our understanding of memory formation and retrieval. Its CA1 region is known for encoding contextual memory. Here, using a computational approach, which embeds existing physiological data, we propose a particular role of ...
Shivendra eTewari, Vladimir eParpura
doaj   +1 more source

Stomatin-like Protein 2 Links Mitochondria to T-Cell Receptor Signalosomes at the Immunological Synapse and Enhances T-Cell Activation [PDF]

, 2007
T cell activation through the antigen receptor (TCR) requires sustained signalling from microclusters in the peripheral region of the immunological synapse (IS).
Joaquin Madrenas, Maria E. Marquez, Mark G. Kirchhof, Isaac Blaca, Peter J. Darlington, Santosh Vardhana, Luan A. Chau, Roy Taylor, Caitlin D. Lemke, Kamilia Rizkalla, Michael L. Dustin   +10 more
core  

ATP Hysteresis in Tripartite Synapses

, 2009
Recent experimental studies strongly suggest the influence of glial purinergic transmission in the modulation of synaptic dynamics. By releasing adenosine triphosphate (ATP), which accumulates as adenosine, astrocytes tonically suppressed synaptic transmission. The delayed multi-step feedback of the glial adenosine with the neuron suggest the existence
openaire   +3 more sources

The Home Under Surveillance: A Tripartite Assemblage

, 2012
The home is perceived as an enclave of privacy and retreat from the proliferation of surveillance technologies in the spaces ofpublic and semi-public life.
Rapoport, Michele (Michal)
core   +1 more source

Ephrins and Eph Receptor Tyrosine Kinases in Synapse Formation

, 2009
Here, we discuss what is known about the function of ephrins and Eph receptors In synapse formation in the peripheral nervous system and central nervous system.
Daniel J. Liebl, Liebl, Daniel J., Krull, Catherine E., Catherine E. Krull   +3 more
core   +1 more source

Astrocyte-Secreted Lcn2 Modulates Dendritic Spine Morphology

Cells
Learning and memory formation rely on synaptic plasticity, the process that changes synaptic strength in response to neuronal activity. In the tripartite synapse concept, molecular signals that affect synapse strength and morphology originate not only ...
Marta Doliwa, Bozena Kuzniewska, Karolina Nader, Patryk Reniewicz, Leszek Kaczmarek, Piotr Michaluk, Katarzyna Kalita   +6 more
doaj   +1 more source

Exploring the synapse

, 2011
Describe the events during the transmission of an impulse across a ...

core