Results 91 to 100 of about 85,493 (199)

MRamirez1414/Cochlear-ribbon-synapse-maturation-requires-Nlgn1-and-Nlgn3: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3

, 2022
Code associated with Cochlear ribbon synapse maturation requires Nlgn1 and ...
MRamirez1414
core   +1 more source

Bisphenol A and Its Analogue Bisphenol S Inhibit Cholinergic Neurotransmission at the Tripartite Colonic Myenteric Synapse of CD1 Mice by Targeting Interstitial Cells of Cajal. [PDF]

Int J Mol Sci
Bisphenol A (BPA) and bisphenol S (BPS) are frequently used in the plastic industry. Despite significant alimentary exposure, their effects on the gastrointestinal (GI) tract remain largely unknown.
Makowska K, Vieira C, Silva I, Aprianto Y, Silva D, Bessa-Andrês C, Lopes A, Gonkowski S, Correia-de-Sá P.   +8 more
europepmc   +2 more sources

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

Anterior Cingulate Cortex Astrocytes Regulate Chronic Itch and Comorbid Negative Emotional Disorders in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
ACC astrocytes are morphologically and functionally activated in DCP‐induced chronic itch. Chemogenetic activation of these astrocytes positively modulates the calcium activity of local CaMKII+ excitatory neurons and the release of D‐serine and ATP, and exerts anti‐pruritic, anxiolytic, and anti‐depressant effects.
Ze Fan, Xiaotong Shi, You Wu, Ningcan Ma, Ziyi Dai, Lisen Wang, Yushan Jin, Yuanyuan Zhu, Yiming Chen, Haopeng Zhang, Hui Zhang, Shengxi Wu, Jing Huang   +12 more
wiley   +1 more source

Ferroelectric Junctionless Double-Gate Silicon-On-Insulator FET as a Tripartite Synapse

In this work, we report the concept and experimentally demonstrate the first tunable ferroelectric (Fe) junctionless (JL) transistor (Fe-JLFET), capable of emulating the functionality of biological tri-partite synapses, which is an artificial three ...
Cavalieri, M., Kamaei, S., Gastaldi, C., Stolichnov, I., Ionescu, A. M., Saeidi, A., Radu, I.   +6 more
core   +1 more source

Bi-directional astrocytic regulation of neuronal activity within a network

Frontiers in Computational Neuroscience, 2012
The concept of a tripartite synapse holds that astrocytes can affect both the pre- and postsynaptic compartments through the Ca2+-dependent release of gliotransmitters.
Susan Yu Gordleeva, Susan Yu Gordleeva, Sergey V Stasenko, Sergey V Stasenko, Alexey V Semyanov, Alexey V Semyanov, Alexander E Dityatev, Alexander E Dityatev, Victor B Kazantsev, Victor B Kazantsev   +9 more
doaj   +1 more source

Spatiotemporal immune heterogeneity and precision immunotherapy for ovarian cancer

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Graphical Highlights Spatiotemporal immune heterogeneity shapes distinct and evolving immune ecosystems in ovarian cancer. Multimodal biomarkers enable biologically informed patient stratification beyond static single‐marker approaches. Precision immunotherapy should match dominant immune barriers across lesions and treatment stages.
Xinfeng Yang, Yida Wang, Haiyue You, Jingyi Gao, Yangkun Feng, Feng Zhang, Yan Zhang, Bing Zhang, Shaojie Zhao, Yanfang Gu   +9 more
wiley   +1 more source

Interaction proteomics of synapse protein complexes [PDF]

, 2010
The brain integrates complex types of information, and executes a wide range of physiological and behavioral processes. Trillions of tiny organelles, the synapses, are central to neuronal communication and information processing in the brain.
Patricia Klemmer, Klemmer, P., Smit, A.B., Ka Wan Li, August B. Smit, Li, K.W., Li, K.W.; id_orcid   +6 more
core   +2 more sources

Astroglial networks and implications for therapeutic neuromodulation of epilepsy

Frontiers in Computational Neuroscience, 2012
Epilepsy is a common chronic neurologic disorder affecting approximately 1 percent of the world population. More than one-third of all epilepsy patients have incompletely controlled seizures or debilitating medication side effects in spite of optimal ...
Mark R Witcher, Thomas L Ellis
doaj   +1 more source

A Microglia–Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses

Glia, Volume 74, Issue 9, September 2026.
Activated microglia‐derived inflammatory signals drive astrocytic Piezo1 expression in both in vitro and in vivo models. Piezo1 upregulation modulates astrocytic Ca2+ dynamics and inflammatory gene expression, thereby limiting microglial activation. ABSTRACT Structural tissue alterations in numerous brain disorders can initiate mechanosensory signaling
Yanyang Bai, Hyun B. Choi, Stefan Wendt, Morgan Towriss, Ada J. Lin, Christopher J. Groten, Ivy Cui, Haakon B. Nygaard, Brian A. MacVicar   +8 more
wiley   +1 more source