Results 101 to 110 of about 85,493 (199)
Neurodegeneration: New Road Leads Back to the Synapse [PDF]
, 2012 Much of Parkinson’s research over the last decade has focused on cellular stress as a candidate mechanism. In this issue of Neuron, a new study by Matta et al.
Heutink, Peter +3 more
core +1 more source
Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells
Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen +6 more
wiley +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
MedComm, Volume 7, Issue 9, September 2026.Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Hemichannels: new roles in astroglial function
Frontiers in Physiology, 2014 The role of astrocytes in brain function has evolved over the last decade, from support cells to active participants in the neuronal synapse through the release of gliotransmitters.
Jimmy eStehberg, Juan Andrés Orellana
doaj +1 more source
RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley +1 more source
Astroglial Glutamate Signaling and Uptake in the Hippocampus
Frontiers in Molecular Neuroscience, 2018 Astrocytes have long been regarded as essentially unexcitable cells that do not contribute to active signaling and information processing in the brain. Contrary to this classical view, it is now firmly established that astrocytes can specifically respond
Christine R. Rose +7 more
doaj +1 more source
Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry
MedComm, Volume 7, Issue 9, September 2026.This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie +7 more
wiley +1 more source
Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila [PDF]
, 1999 Glued1 (Gl1) mutants produce a truncated protein that acts as a poison subunit and disables the cytoplasmic retrograde motor dynein. Heterozygous mutants have axonal defects in the adult eye and the nervous system.
Allen, Marcus J. +7 more
core
Astrocyte alterations in α-synucleinopathies
Frontiers in Cellular NeuroscienceDespite long being considered to be passive and supportive cells, in the last decades astrocytes have arisen as key regulators of neuronal excitability, synaptic transmission and plasticity.
Manuela Rodríguez-Castañeda +9 more
doaj +1 more source
Geometrically repatterned immunological synapses uncover formation mechanisms [PDF]
, 2006 The interaction of T cells and antigen-presenting cells is central to adaptive immunity and involves the formation of immunological synapses in many cases.
Michael Meyer-Hermann +5 more
core +2 more sources