Noncanonical Roles of tRNAs: tRNA Fragments and Beyond [PDF]
Annual Review of Genetics, 2020 Zhangli Su, , Anindya Dutta
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Inferring targeting modes of Argonaute-loaded tRNA fragments [PDF]
RNA Biology, 2020 Andrey Grigoriev
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Transfer RNA-Derived Fragments, the Underappreciated Regulatory Small RNAs in Microbial Pathogenesis
Frontiers in Microbiology, 2021 In eukaryotic organisms, transfer RNA (tRNA)-derived fragments have diverse biological functions. Considering the conserved sequences of tRNAs, it is not surprising that endogenous tRNA fragments in bacteria also play important regulatory roles.
Zhongyou Li, Bruce A. Stanton
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Stress Response in Entamoeba histolytica Is Associated with Robust Processing of tRNA to tRNA Halves
mBio, 2023 tRNA-derived fragments have been reported in many different organisms and have diverse cellular roles, such as regulating gene expression, inhibiting protein translation, silencing transposable elements, and modulating cell proliferation.
Manu Sharma +3 more
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Dysregulation of different classes of tRNA fragments in chronic lymphocytic leukemia [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2019 Thomas Kipps +2 more
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Mitochondrial tRNA-Derived Fragments and Their Contribution to Gene Expression Regulation
Frontiers in Physiology, 2021 Mutations in human mitochondrial tRNAs (mt-tRNAs) are responsible for several and sometimes severe clinical phenotypes, classified among mitochondrial diseases.
Athanasios-Nasir Shaukat +3 more
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tRFs and tRNA Halves: Novel Cellular Defenders in Multiple Biological Processes
Current Issues in Molecular Biology, 2022 tRNA fragments derived from angiogenin or Dicer cleavage are referred to as tRNA-derived fragments (tRFs) and tRNA halves. tRFs and tRNA halves have been identified in both eukaryotes and prokaryotes and are precisely cleaved at specific sites on either ...
Jiani Hou +3 more
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Plasma tRNA Fragments Derived from 5′ Ends as Novel Diagnostic Biomarkers for Early-Stage Breast Cancer [PDF]
Molecular Therapy - Nucleic Acids, 2020 Xiaoan Liu, Xinrui Mao
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Emerging roles of tRNA-derived fragments in cancer
Molecular Cancer, 2023 tRNA-derived fragments (tRFs) are an emerging category of small non-coding RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance in high-throughput sequencing has contributed to the identification of increasing number of ...
Min Fu +7 more
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Frontiers in Genetics, 2022 Background: As couples struggle with infertility and livestock producers wish to rapidly improve genetic merit in their herd, assisted reproductive technologies (ART) have become increasingly popular in human medicine as well as the livestock industry ...
Anna K. Goldkamp +3 more
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