Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel. [PDF]
EMBO Rep, 2022 Gaspar CJ +7 more
europepmc +1 more source
Responsive Materials, EarlyView.This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang +6 more
wiley +1 more source
TRP channel expression correlates with the epithelial-mesenchymal transition and high-risk endometrial carcinoma. [PDF]
Cell Mol Life Sci, 2021 Van den Eynde C +12 more
europepmc +1 more source
Harnessing the Folding of Antitumor Peptides for Controlled Carrier‐Free Drug Delivery
Small, EarlyView.A disulfide‐bridged stapled p53 α‐helix co‐assembled with doxorubicin into protease‐resistant nanocomplexes. Reductive intracellular conditions induced helix refolding and nanostructure disassembly, which enabled the coordinated release of the chemotherapeutic agent and anticancer peptide.
Jae Yun Lee +9 more
wiley +1 more source
Comprehensive Analysis of TRP Channel-Related Genes in Patients With Triple-Negative Breast Cancer for Guiding Prognostic Prediction. [PDF]
Front Oncol, 2022 Zhang H +8 more
europepmc +1 more source
Small Methods, EarlyView.This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo +7 more
wiley +1 more source
Understanding the role of Ca2+ via transient receptor potential (TRP) channel in viral infection: Implications in developing future antiviral strategies. [PDF]
Virus Res, 2023 Kumar PS +5 more
europepmc +1 more source
Label‐Free YaxAB Nanopore Fingerprinting of Cancer‐Associated Single‐Residue Bcl‐xL Variants
Small Methods, EarlyView.A YaxAB nanopore workflow enables label‐free single‐molecule fingerprinting of Bcl‐xL variants. Combined normalized current blockade and noise features generated reproducible current fingerprints for wild‐type Bcl‐xL and the cancer‐associated N136K and R165W variants across independent pores, with WT and N136K remaining distinct despite a mass ...
Minji Chung +5 more
wiley +1 more source
A Review on the Role of TRP Channels and Their Potential as Drug Targets_An Insight Into the TRP Channel Drug Discovery Methodologies. [PDF]
Front Pharmacol, 2022 Fallah HP +9 more
europepmc +1 more source