Results 141 to 150 of about 1,264,013 (289)

Modification of the TRP Channel TRPA1 as a Relevant Factor in Migraine-Related Intracranial Hypersensitivity. [PDF]

Int J Mol Sci, 2023
Masood T, Lakatos S, Rosta J.
europepmc   +1 more source

Evolution of free amino acids and volatile compounds in dry‐cured fermented 'salchichón' sausages superficially inoculated with different molds

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Surface molds contribute to flavor development in dry‐cured fermented sausages through their effects on proteolysis, amino acid catabolism, and volatile compound formation. This study evaluated the influence of Aspergillus oryzae, Penicillium camemberti, Penicillium roqueforti and Penicillium nalgiovense on the evolution of free ...
José María Martín‐Miguélez, Alberto González‐Mohino, Jorge Ruiz‐Carrascal, Lary Souza Olegario, Josué Delgado   +4 more
wiley   +1 more source

Structural diversity of heat-sensing channel TRPV3 with Olmsted syndrome mutations

Nature Communications
Mutations in TRPV3, a temperature-sensitive ion channel critical for skin physiology, cause severe genodermatosis called Olmsted syndrome (OS). Here we integrate single-channel recordings and cryo-EM to characterize five OS mutants.
Jeffrey Khau, Rutambhara Purohit, Kirill D. Nadezhdin, Irina A. Talyzina, Alexander I. Sobolevsky   +4 more
doaj   +1 more source

Role of transient receptor potential (TRP) channels in osteoarthritis: a comprehensive review

Frontiers in Pharmacology
Osteoarthritis (OA) is a chronic degenerative joint disease, primarily characterized by the degeneration of articular cartilage, synovial inflammation, and persistent pain, which severely impairs the quality of life for hundreds of millions of patients ...
Pengyan Qiao, Wei Wang, Sumiao Liu, Yanli Yang, Pingzhi Wang, Yang Liu, Yazhen Su, Peng Hu, Jie Pan, Liyun Zhang   +9 more
doaj   +1 more source

Identification of a TRP channel-related risk model for predicting prognosis and therapeutic effects of patients with hepatocellular carcinoma. [PDF]

J Cancer Res Clin Oncol, 2023
Pang C, Xu Z, Han J, Li F, Zhu H, Zhang J, Wang D, Xu X.   +7 more
europepmc   +1 more source

Supraglottic Botulinum Toxin Injection Improves Symptoms of Laryngeal Sensory Dysfunction

The Laryngoscope, EarlyView.
In this retrospective cohort of 80 patients with refractory laryngeal sensory symptoms, supraglottic botulinum toxin type A significantly improved Laryngeal Hypersensitivity Questionnaire, Reflux Symptom Index, and Cough Severity Index scores at a mean of 5.2 weeks, while Voice Handicap Index‐10 scores remained unchanged.
Daniel Novakovic, Katrina Sandham, Thomas Emslie Stewart, James Jordan Johnston   +3 more
wiley   +1 more source

Genome-Wide Characterization and Gene Expression Analysis of TRP Channel Superfamily Genes in the Migratory Locust, Locusta migratoria. [PDF]

Genes (Basel), 2023
Yang Y, Guo W, Wang M, Zhang D.
europepmc   +1 more source

Participação dos receptores glutamatérgicos e dos receptores de potencial transitório na ação antinociceptiva do (-)-Linalol [PDF]

, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010O objetivo do presente trabalho foi o de estender e confirmar a ação antinociceptiva do (-)-linalol ...
Batista, Patrícia Aparecida
core  

ATXN8OS Intermediate Expansion Acts as a Genetic Modifier in Spinocerebellar Ataxia Type 48 (SCA48/STUB1)

Movement Disorders, EarlyView.
Abstract Background Association between monoallelic STUB1 variant and expanded ATXN8OS alleles was recently reported, suggesting a pathogenic interaction that may influence spinocerebellar ataxia type 48 (SCA48) phenotype. Objectives We investigated the frequency and clinical impact of ATXN8OS in a large cohort of STUB1 carriers compared to individuals
Charlotte Mouraux, Jean‐Loup Méreaux, Claire‐Sophie Davoine, Léna Guillot Noel, Emilien Petit, Quentin Thomas, Adem Nasraoui, Anna Heinzmann, Claire Ewenczyk, Alexis Brice, Alexandra Durr, Giulia Coarelli   +11 more
wiley   +1 more source

EMC is required for biogenesis of Xport-A, an essential chaperone of Rhodopsin-1 and the TRP channel. [PDF]

EMBO Rep, 2022
Gaspar CJ, Vieira LC, Santos CC, Christianson JC, Jakubec D, Strisovsky K, Adrain C, Domingos PM.   +7 more
europepmc   +1 more source