Results 151 to 160 of about 35,655 (260)

Shear-induced ciliary autotomy mediated by a TRP channel and a voltage-dependent calcium channel. [PDF]

open access: yesiScience
Hui S   +6 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Forty sites of TRP channel regulation. [PDF]

open access: yesCurr Opin Chem Biol
Talyzina IA   +2 more
europepmc   +1 more source

Effects of Pistacia lentiscus Leaf‐Twig and Resin (Mastic) Oils on Salivary Flow in Healthy Individuals

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Pistacia lentiscus L. tree is known for its aromatic mastic gum containing terpenes α‐pinene and β‐myrcene, and has been applied as a traditional remedy in oral care for centuries. Previously, intranasal exposure to mastic resin volatiles increased salivary flow in healthy and dry‐mouth individuals. This study assessed the biological
Wiktoria Potocka   +4 more
wiley   +1 more source

Inhibitory Effect of Evodiamine on Psoriasis Lesions and Itching in Mice

open access: yesClinical, Cosmetic and Investigational Dermatology
Jianqiang Liang,1,* Weixiong Chen,2,* Yanhui Zhou,3 Weijia Meng,3 Man Xie,3 Yunying Weng,1 Luxuan Qin,1 Jianmin Li,4 Guanyi Wu1,5,6 1College of Basic Medicine, Guangxi University of Chinese Medicine, Nanning, People’s Republic of China; 2School ...
Liang J   +8 more
doaj  

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao   +12 more
wiley   +1 more source

Ascorbate-induced oxidative stress mediates TRP channel activation and cytotoxicity in human etoposide-sensitive and -resistant retinoblastoma cells. [PDF]

open access: yesLab Invest, 2021
Oronowicz J   +9 more
europepmc   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng   +10 more
wiley   +1 more source

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