Results 151 to 160 of about 1,329,018 (250)

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

A novel mechanism of imeglimin-mediated insulin secretion via the cADPR-TRP channel pathway. [PDF]

J Diabetes Investig, 2022
Funazaki S, Yoshida M, Yamada H, Kakei M, Kawakami M, Nagashima S, Hara K, Dezaki K.   +7 more
europepmc   +1 more source

Where Eastern Medicine Meets Western Medicine: A World Review of the Management of Chronic Cough

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose To summarize current Western and Eastern approaches to the evaluation and management of chronic cough, with particular emphasis on etiology‐directed therapy, cough hypersensitivity, behavioral interventions, neuromodulators, procedural treatments, and traditional remedies.
Thomas Zheng Jie Teng, Zhi Xuan Koh, Justin Yi Shen Lim, Kavimalar Ravi, Jin Wayne Kyler Ong, Christina Hui Lee Ng   +5 more
wiley   +1 more source

Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca²⁺-calmodulin binding. [PDF]

J Biol Chem, 2021
Amini M, Chang Y, Wissenbach U, Flockerzi V, Schlenstedt G, Beck A.   +5 more
europepmc   +1 more source

Geographical Variation in Thermal Adaptation of the Asiatic Toad (Bufo gargarizans)

Integrative Zoology, EarlyView.
Northern and southern populations of Bufo gargarizans exhibit coordinated divergence in thermal preference, resting metabolic rate, and TRPM4 temperature sensitivity along a climatic gradient. ABSTRACT Thermal adaptation in animals can manifest in multiple dimensions, yet few studies have integrated behavioral, physiological, and molecular perspectives
Longcheng Fan, Yonghua Wu
wiley   +1 more source

Relationship between sensory irritation on skin surface and TRP channel activation. [PDF]

J Physiol Sci
Fujita F, Takaishi M, Iwashita S, Yoshikawa K, Sawada M, Shimizu H, Nagamatsu M, Shiomi Y, Hara T, Ishida K, Uchida K, Suzuki Y, Tominaga M.   +12 more
europepmc   +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg, Julie van Waterschoot, Mathilde Moyaert, Adam Chaker, Philippe Gevaert, Jan Hagemann, Valérie Hox, Maarten Kleijwegt, Ludger Klimek, Devyani Lal, Juan Maza‐Solano, Oliver Pfaar, Fabio Simon Ryser, Michele Shiappoli, Diana Silva, Sanna Toppila‐Salmi, Johanna Wikstén, Sietze Reitsma, Laura Van Gerven   +18 more
wiley   +1 more source

Light-induced remodeling of the <i>Drosophila</i> phosphoproteome regulates visual adaptation through the Trp channel. [PDF]

Sci Signal
Kramer LD, Brandwine-Shemmer T, Pierce LR, Liu YK, Bartels JP, Huber A, Minke B, Tao WA, Weake VM.   +8 more
europepmc   +1 more source

Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel. [PDF]

Nat Struct Mol Biol, 2021
Nadezhdin KD, Neuberger A, Trofimov YA, Krylov NA, Sinica V, Kupko N, Vlachova V, Zakharian E, Efremov RG, Sobolevsky AI.   +9 more
europepmc   +1 more source