Results 161 to 170 of about 886,471 (280)

Bidirectional crosstalk between TRP channels and Toll-like receptors in inflammation and host defense. [PDF]

J Neuroinflammation
Zeng Q, Zhang C, Xie N, Chen S, Liu C, Luo H, You X.   +6 more
europepmc   +1 more source

TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? [PDF]

Membranes (Basel), 2023
Soussi M, Hasselsweiller A, Gkika D.
europepmc   +1 more source

Ecological variability of Hippopotamus antiquus from the late Early–Middle Pleistocene of Megalopolis Basin (Greece): Evidence for dynamic habitats in a glacial microrefugium

Boreas, EarlyView.
This study investigates the ecology of the extinct European Hippopotamus from the late Early–Middle Pleistocene (c. 900–400 ka) sequence of the Megalopolis Basin, a glacial microrefugium for temperate taxa in southern Greece. Using stable carbon (δ13C) and oxygen (δ18O) isotope analyses and microwear analyses of Hippopotamus dental elements, we ...
Effrosyni Roditi, Gabriele Russo, Hervé Bocherens, George E. Konidaris, Athanassios Athanassiou, Florent Rivals, Vangelis Tourloukis, Eleni Panagopoulou, Panagiotis Karkanas, Katerina Harvati   +9 more
wiley   +1 more source

Identification of 14-3-3 Proteins as Binding Partners of TRP Channels. [PDF]

J Chem Inf Model
Peña-Vilches N, González-Avendaño M, Soto-García N, Maureira D, Silva I, Avilés J, Manríquez-Benítez E, Medina E, Cerda O, Galaz-Davison P, Vergara-Jaque A.   +10 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Emerging Role of TRP Channels in Osteoarthritis Pathogenesis. [PDF]

Cells
Yadav S, Yadav J, Humphrey MB.
europepmc   +1 more source

Role of TRP Channels in Liver-Related Diseases. [PDF]

Int J Mol Sci, 2023
Liu Y, Lyu Y, Zhu L, Wang H.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Sepsis-associated acute lung injury: do inflammatory lipid mediators flood the lungs by activating pulmonary TRP channels? [PDF]

Intensive Care Med Exp
Birkic N, Ehrman RR, Grbeša ĐC, Minic Z, Reynolds CA.   +4 more
europepmc   +1 more source