Results 151 to 160 of about 852,547 (280)

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg, Julie van Waterschoot, Mathilde Moyaert, Adam Chaker, Philippe Gevaert, Jan Hagemann, Valérie Hox, Maarten Kleijwegt, Ludger Klimek, Devyani Lal, Juan Maza‐Solano, Oliver Pfaar, Fabio Simon Ryser, Michele Shiappoli, Diana Silva, Sanna Toppila‐Salmi, Johanna Wikstén, Sietze Reitsma, Laura Van Gerven   +18 more
wiley   +1 more source

From mechanotransduction to manual therapy: advances in piezo/TRP channels and lumbar degeneration. [PDF]

Front Physiol
Liu Z, Peng T, Li W, Zhu M.
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Nanoparticles-Mediated Modulation of TRP Channels: Advances and Therapeutic Potential. [PDF]

Wiley Interdiscip Rev Nanomed Nanobiotechnol
Foster KA, Midler N, Shine O, Rosenfeld D.   +3 more
europepmc   +1 more source

TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? [PDF]

Membranes (Basel), 2023
Soussi M, Hasselsweiller A, Gkika D.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Identification of 14-3-3 Proteins as Binding Partners of TRP Channels. [PDF]

J Chem Inf Model
Peña-Vilches N, González-Avendaño M, Soto-García N, Maureira D, Silva I, Avilés J, Manríquez-Benítez E, Medina E, Cerda O, Galaz-Davison P, Vergara-Jaque A.   +10 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Emerging Role of TRP Channels in Osteoarthritis Pathogenesis. [PDF]

Cells
Yadav S, Yadav J, Humphrey MB.
europepmc   +1 more source

Role of TRP Channels in Liver-Related Diseases. [PDF]

Int J Mol Sci, 2023
Liu Y, Lyu Y, Zhu L, Wang H.
europepmc   +1 more source