Results 231 to 240 of about 886,471 (280)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Thermo‐tone: A newly revealed mechanism of blood flow regulation

Experimental Physiology, EarlyView.
Abstract Myogenic tone enables dynamic control of tissue blood flow. This intrinsic property of vascular smooth muscle cells to sense stretch and reflexively adjust the calibre of small arteries is crucial to maintain capillary pressure and a blood flow reserve. For over 120 years blood pressure was considered the sole determinant of myogenic tone. Our
Thieu X. Phan, Gerard P. Ahern
wiley   +1 more source

TRP channels: a provocative rationalization for local Ca²⁺ control in arterial tone development. [PDF]

Front Physiol
El-Lakany MA, Welsh DG.
europepmc   +1 more source

Role of thermosensitive transient receptor potential (TRP) channels in thermal preference of male and female mice. [PDF]

J Therm Biol
Carstens MI, Mahroke A, Selescu T, Carstens E.   +3 more
europepmc   +1 more source

Thermal gradient ring for analysis of temperature-dependent behaviors involving TRP channels in mice. [PDF]

J Physiol Sci
Ujisawa T, Lei J, Kashio M, Tominaga M.
europepmc   +1 more source

Thermosensitive TRP Channels Are Functionally Expressed and Influence the Lipogenesis in Human Meibomian Gland Cells. [PDF]

Int J Mol Sci
Keller M, Mergler S, Li A, Zahn I, Paulsen F, Garreis F.   +5 more
europepmc   +1 more source

TRP Channels and Analgesia [PDF]

Life Sciences, 2013
Since cloning and characterizing the first nociceptive ion channel Transient Receptor Potential (TRP) Vanilloid 1 (TRPV1), other TRP channels involved in nociception have been cloned and characterized, which include TRP Vanilloid 2 (TRPV2), TRP Vanilloid 3 (TRPV3), TRP Vanilloid 4 (TRPV4), TRP Ankyrin 1 (TRPA1) and TRP Melastatin 8 (TRPM8), more ...
Louis S Premkumar
exaly   +3 more sources

TRP Channels as Potential Drug Targets

Annual Review of Pharmacology and Toxicology, 2018
The transient receptor potential (TRP) superfamily of channels comprises a diverse group of cation channels. Four TRP channel subunits coassemble to form functional homo- or heterotetramers that pass sodium, calcium, or both in the inward direction ...
Magdalene M Moran
exaly   +2 more sources

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TRP channels

Current Opinion in Pharmacology, 2015
Evidence is accumulating on the role of transient receptor potential (TRP) channels, namely TRPV1, TRPA1, TRPV4 and TRPM8, expressed by C- and Aδ-fibres primary sensory neurons, in cough mechanism. Selective stimuli for these channels have been proven to provoke and, more rarely, to inhibit cough.
BENEMEI, SILVIA, Patacchini, R, TREVISANI, MARCELLO, GEPPETTI, PIERANGELO   +3 more
openaire   +2 more sources

TRP channels and mice deficient in TRP channels

Pflügers Archiv - European Journal of Physiology, 2005
Transient receptor potential (TRP) channels are a superfamily of functionally versatile cation-permeant ion channels present in almost all mammalian cell types. Although they were initially proposed as store-operated calcium channels, recent progress shows that they exhibit a variety of regulatory and functional themes.
Bimal N, Desai, David E, Clapham
openaire   +2 more sources