Results 231 to 240 of about 852,547 (280)

Role of TRP channels in carcinogenesis and metastasis: Pathophysiology and regulation by non-coding RNAs. [PDF]

open access: yesNoncoding RNA Res
Turgambayeva A   +6 more
europepmc   +1 more source

TRP channels and analgesia [PDF]

open access: yesLife Sciences, 2013
Since cloning and characterizing the first nociceptive ion channel Transient Receptor Potential (TRP) Vanilloid 1 (TRPV1), other TRP channels involved in nociception have been cloned and characterized, which include TRP Vanilloid 2 (TRPV2), TRP Vanilloid 3 (TRPV3), TRP Vanilloid 4 (TRPV4), TRP Ankyrin 1 (TRPA1) and TRP Melastatin 8 (TRPM8), more ...
Louis S Premkumar
exaly   +3 more sources

TRP Channels as Potential Drug Targets

open access: yesAnnual Review of Pharmacology and Toxicology, 2018
The transient receptor potential (TRP) superfamily of channels comprises a diverse group of cation channels. Four TRP channel subunits coassemble to form functional homo- or heterotetramers that pass sodium, calcium, or both in the inward direction ...
Magdalene Moran
exaly   +2 more sources

Steroids and TRP Channels: A Close Relationship

open access: yesInternational Journal of Molecular Sciences, 2020
Transient receptor potential (TRP) channels are remarkable transmembrane protein complexes that are essential for the physiology of the tissues in which they are expressed.
Tamara Rosenbaum   +2 more
exaly   +2 more sources

TRP channels

Current Opinion in Pharmacology, 2015
Evidence is accumulating on the role of transient receptor potential (TRP) channels, namely TRPV1, TRPA1, TRPV4 and TRPM8, expressed by C- and Aδ-fibres primary sensory neurons, in cough mechanism. Selective stimuli for these channels have been proven to provoke and, more rarely, to inhibit cough.
BENEMEI, SILVIA   +3 more
openaire   +2 more sources

TRP channels and mice deficient in TRP channels

Pflügers Archiv - European Journal of Physiology, 2005
Transient receptor potential (TRP) channels are a superfamily of functionally versatile cation-permeant ion channels present in almost all mammalian cell types. Although they were initially proposed as store-operated calcium channels, recent progress shows that they exhibit a variety of regulatory and functional themes.
Bimal N, Desai, David E, Clapham
openaire   +2 more sources

TRP Channels and Pain

Current Pharmaceutical Design, 2009
Preclinical research has identified an array of ion channels in sensory neurons involved in the generation and transduction of pain as potential targets for pharmacological intervention. Paramount among these new targets is the family of thermosensitive transient receptor potential channels, referred to as "thermoTRPs".
Daniel N, Cortright, Arpad, Szallasi
openaire   +2 more sources

TRP Channels

Comprehensive Physiology, 2012
Abstract TRP channels constitute a large superfamily of cation channel forming proteins, all related to the gene product of the transient receptor potential ( trp ) locus in Drosophila .
Maarten, Gees   +3 more
openaire   +2 more sources

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