Results 241 to 250 of about 852,547 (280)
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2010
Microbes have made numerous contributions to the study of biology and medicine. Those contributions also include many original discovery's in the study of ion channels often thought as the province of neuroscientists or cardiophysiologists. Yeast have long been used as a model organism and TRP channel genes and their transmembrane products touted as ...
Marta, Kaleta, Christopher, Palmer
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Microbes have made numerous contributions to the study of biology and medicine. Those contributions also include many original discovery's in the study of ion channels often thought as the province of neuroscientists or cardiophysiologists. Yeast have long been used as a model organism and TRP channel genes and their transmembrane products touted as ...
Marta, Kaleta, Christopher, Palmer
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2010
A wide range of single- and multi-cellular parasites infect humans and other animals, causing some of the most prevalent and debilitating diseases on the planet. There have been virtually no published studies on the TRP channels of this diverse group of organisms.
Wolstenholme AJ +2 more
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A wide range of single- and multi-cellular parasites infect humans and other animals, causing some of the most prevalent and debilitating diseases on the planet. There have been virtually no published studies on the TRP channels of this diverse group of organisms.
Wolstenholme AJ +2 more
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Science's STKE, 2005
The mammalian TRP (transient receptor potential) family consists of six main subfamilies termed the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and TRPA (ankyrin) groups. These subfamilies encompass 28 ion channels that function as diverse cellular sensors.
Bernd, Nilius +2 more
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The mammalian TRP (transient receptor potential) family consists of six main subfamilies termed the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and TRPA (ankyrin) groups. These subfamilies encompass 28 ion channels that function as diverse cellular sensors.
Bernd, Nilius +2 more
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TRP channels in mechanosensation
Current Opinion in Neurobiology, 2005Channels of the TRP superfamily have sensory roles in a wide variety of receptor cells, especially in mechanosensation. In some cases, the channels appear to be directly activated by mechanical force; in others, they appear to be downstream of a messenger pathway initiated by force on a non-channel sensor.
Shuh-Yow, Lin, David P, Corey
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Current Drug Target -CNS & Neurological Disorders, 2004
Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Noxious thermal, mechanical, or chemical stimuli evoke pain through excitation of the peripheral terminals called nociceptor, and many kinds of ionotropic and metabotropic receptors are involved in this process. Capsaicin receptor TRPV1 is a nociceptor-specific ion channel that serves as the molecular target of capsaicin.
Mitsuko, Numazaki, Makoto, Tominaga
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Role of TRP channels in the cardiovascular system
American Journal of Physiology - Heart and Circulatory Physiology, 2015 The transient receptor potential (TRP) superfamily consists of a large number of nonselective cation channels with variable degree of Ca(2+)-permeability.
Lixia Yue, Jianyang Du
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2017
The transient receptor potential (TRP) ion channels are named after the discovery of the photo-transducted channels in Drosophila. TRPs, activated by various extracellular and intracellular stimuli, play a plethora of physiological and pathological roles.
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The transient receptor potential (TRP) ion channels are named after the discovery of the photo-transducted channels in Drosophila. TRPs, activated by various extracellular and intracellular stimuli, play a plethora of physiological and pathological roles.
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An Introduction on TRP Channels
2007The transient receptor potential (TRP) ion channels are named after the role of the channels in Drosophila phototransduction. Mammalian TRP channel subunit proteins are encoded by at least 28 genes. TRP cation channels display an extraordinary assortment of selectivities and activation mechanisms, some of which represent previously unrecognized modes ...
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2007
TRP proteins form ion channels that are activated following receptor stimulation. Several members of the TRP family are likely to be expressed in lymphocytes. However, in many studies, messenger RNA (mRNA) but not protein expression was analyzed and cell lines but not primary human or murine lymphocytes were used.
E C, Schwarz +6 more
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TRP proteins form ion channels that are activated following receptor stimulation. Several members of the TRP family are likely to be expressed in lymphocytes. However, in many studies, messenger RNA (mRNA) but not protein expression was analyzed and cell lines but not primary human or murine lymphocytes were used.
E C, Schwarz +6 more
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AN INTRODUCTION TO TRP CHANNELS
Annual Review of Physiology, 2006▪ Abstract The aim of this review is to provide a basic framework for understanding the function of mammalian transient receptor potential (TRP) channels, particularly as they have been elucidated in heterologous expression systems. Mammalian TRP channel proteins form six-transmembrane (6-TM) cation-permeable channels that may be grouped into six ...
I Scott, Ramsey +2 more
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