Ultra-wideband transmitter design based on a new transmitted reference pulse cluster
ICT Express, 2017 This study presents an energy efficient ultra-wideband (UWB) transmitter based on the novel transmitted reference pulse cluster (TRPC) modulation scheme.
Yiming Huo, Xiaodai Dong, Ping Lu
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Abnormal expression, localization and interaction of canonical transient receptor potential ion channels in human breast cancer cell lines and tissues: a potential target for breast cancer diagnosis and therapy [PDF]
Cancer Cell International, 2009 Background Ca2+ is known to be involved in a number of metastatic processes including motility and proliferation which can result in store-depletion of Ca2+.
Djamgoz Mustafa +3 more
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The photoswitchable cannabinoid azo-HU308 enables optical control of Ca<sup>2+</sup> dynamics in INS-1 β-cells via off-target effects on TRPC channels. [PDF]
FEBS Open BioLight activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Viray AEG, Frank JA.
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TRPC channel activation by extracellular thioredoxin [PDF]
Nature, 2008 Mammalian homologues of Drosophila melanogaster transient receptor potential (TRP) are a large family of multimeric cation channels that act, or putatively act, as sensors of one or more chemical factor. Major research objectives are the identification of endogenous activators and the determination of cellular and tissue functions of these channels ...
Shang‐Zhong Xu +16 more
openalex +5 more sources
Frontiers in Cell and Developmental Biology, 2021 The seven canonical members of transient receptor potential (TRPC) proteins form cation channels that evoke membrane depolarization and intracellular calcium concentration ([Ca2+]i) rise, which are not only important for regulating cell function but ...
Jaepyo Jeon +12 more
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Insights into Activation Mechanisms of Store-Operated TRPC1 Channels in Vascular Smooth Muscle. [PDF]
, 2020 In vascular smooth muscle cells (VMSCs), the stimulation of store-operated channels (SOCs) mediate Ca2+ influx pathways which regulate important cellular functions including contraction, proliferation, migration, and growth that are associated with the ...
Albert, AP +3 more
core +1 more source
Role of Transient Receptor Potential Canonical Channels in Heart Physiology and Pathophysiology
Frontiers in Cardiovascular Medicine, 2020 Transient receptor potential canonical (TRPC) channels are involved in the regulation of cardiac function under (patho)physiological conditions and are closely associated with the pathogenesis of cardiac hypertrophy, arrhythmias, and myocardial ...
Hairuo Wen +3 more
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Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
, 2014 Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
core +9 more sources
Transient Receptor Potential Canonical Channels in Health and Disease: A 2020 Update
Cells, 2021 This 2020 Special Issue “TRPC channels” of Cells was dedicated to commemorating the 25th anniversary of discovery of the Transient Receptor Potential Canonical (TRPC) channel subfamily [...]
Priya R. Kirtley +3 more
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Inhibition of diacylglycerol-sensitive TRPC channels by synthetic and natural steroids. [PDF]
PLoS ONE, 2012 TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca(2+) signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition have ...
Susanne Miehe +8 more
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