Results 41 to 50 of about 18,800 (265)

Dynamics of receptor-operated Ca2+ Currents Through TRPC Channels Controlled via the PI(4,5)P2-PLC Signaling Pathway

Frontiers in Pharmacology, 2015
Transient receptor potential canonical (TRPC) channels are Ca2+-permeable, nonselective cation channels that carry receptor-operated Ca2+ currents (ROCs) triggered by receptor-induced, phospholipase C (PLC)-catalyzed hydrolysis of phosphatidylinositol 4 ...
Masayuki X Mori, Kyohei eItsuki, Hideharu eHase, Seishirou eSawamura, Tatsuki eKurokawa, Yasuo eMori, Ryuji eInoue   +6 more
doaj   +1 more source

Involvement of TRPC channels in lung cancer cell differentiation and the correlation analysis in human non-small cell lung cancer. [PDF]

PLoS ONE, 2013
The canonical transient receptor potential (TRPC) channels are Ca(2+)-permeable cationic channels controlling the Ca(2+) influx evoked by G protein-coupled receptor activation and/or by Ca(2+) store depletion. Here we investigate the involvement of TRPCs
Hong-Ni Jiang, Bo Zeng, Yi Zhang, Nikoleta Daskoulidou, Hong Fan, Jie-Ming Qu, Shang-Zhong Xu   +6 more
doaj   +1 more source

Ethnic and geographic differentiation of helicobacter pylori within Iran [PDF]

, 2010
The bacterium Helicobacter pylori colonizes the human stomach, with individual infections persisting for decades. The spread of the bacterium has been shown to reflect both ancient and recent human migrations. We have sequenced housekeeping genes from H.
Latifi-Navid, Saeid, Ghorashi, Seyed Ali, Siavoshi, Farideh, Linz, Bodo, Massarrat, Sadegh, Khegay, Tanya, Salmanian, Ali-Hatef, Shayesteh, Ali Akbar, Masoodi, Mohsen, Ghanadi, Koroush, Ganji, Azita, Suerbaum, Sebastian, Achtman, Mark, Malekzadeh, Reza, Falush, Daniel   +14 more
core   +2 more sources

How TRPC Channels Modulate Hippocampal Function [PDF]

International Journal of Molecular Sciences, 2020
Transient receptor potential canonical (TRPC) proteins constitute a group of receptor-operated calcium-permeable nonselective cationic membrane channels of the TRP superfamily. They are largely expressed in the hippocampus and are able to modulate neuronal functions.
Roberta Gualdani, Philippe Gailly
openaire   +3 more sources

TRPC expression in human periodontal ligament cells and the periodontal tissue of periodontitis mice: a preliminary study

Laboratory Animal Research, 2023
Background Transient receptor potential canonical (TRPC) channels are non-selective cationic channels with permeability to Ca2+ and Na+. Despite their importance, there are currently few studies on TRPC in the periodontal ligament (PDL) and bone cells in
Aeryun Kim, Ae Ri Kim, Yeong-Eui Jeon, Yun‑Jung Yoo, Yu-Mi Yang, Eun‑Jung Bak   +5 more
doaj   +1 more source

The impact of tire rubber powder contaminants on the physical properties of loess

Frontiers in Environmental Science
With the development of industry and the popularization of automobiles, a large number of tires are produced globally every year, and the tire rubber powder contaminants (TRPC) generated by the friction with the ground during the driving of automobiles ...
Shaoli Liu, Qiang Sun, Qiang Sun, Qiang Sun, Pengda Ma, Rui Lv, He Zhang, Jingjing Nan, Jingjing Nan   +8 more
doaj   +1 more source

Pathophysiological Role of Caveolae in Hypertension [PDF]

, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver, Gollasch, Maik, Kaßmann, Mario, Lian, Xiaoming, Matthaeus, Claudia   +4 more
core   +2 more sources

Light-Mediated Control over TRPC3-Mediated NFAT Signaling

Cells, 2020
Canonical transient receptor potential (TRPC) channels were identified as key players in maladaptive remodeling, with nuclear factor of activated T-cells (NFAT) transcription factors serving as downstream targets of TRPC-triggered Ca2+ entry in these ...
Annarita Graziani, Bernadett Bacsa, Denis Krivic, Patrick Wiedner, Sanja Curcic, Rainer Schindl, Oleksandra Tiapko, Klaus Groschner   +7 more
doaj   +1 more source

CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity

Molecular Metabolism, 2022
Objective: Proopiomelanocortin (POMC) neurons are the key anorexigenic hypothalamic neuron for integrating metabolic cues to generate the appropriate output for maintaining energy homeostasis and express the requisite channels as a perfect synaptic ...
Jian Qiu, Martha A. Bosch, Todd L. Stincic, Avery C. Hunker, Larry S. Zweifel, Oline K. Rønnekleiv, Martin J. Kelly   +6 more
doaj   +1 more source

A Verified Information-Flow Architecture [PDF]

, 2016
SAFE is a clean-slate design for a highly secure computer system, with pervasive mechanisms for tracking and limiting information flows. At the lowest level, the SAFE hardware supports fine-grained programmable tags, with efficient and flexible ...
Collins, Nathan, de Amorim, Arthur Azevedo, DeHon, André, Demange, Delphine, Hritcu, Catalin, Pichardie, David, Pierce, Benjamin C., Pollack, Randy, Tolmach, Andrew   +8 more
core   +5 more sources