Results 111 to 120 of about 7,904 (196)

Three cases of steroid resistant nephrotic syndrome associated with gene mutation of transient receptor potential cation channel 6(TRPC 6)in children

open access: yes, 2020
原发性肾病综合征中大约有20%的患儿出现激素耐药,其中局灶节段硬化(focal segmental glomerulosclerosis,FSGS)是其主要的病理改变,且多发生于6岁前,并在10岁内进展为ESRD[1-2]。目前已明确多种基因的突变参与FSGS的形成,尤其是编码足细胞相关蛋白的单基因突变在其中发挥重要作用[3]。
SHI Zhuo   +4 more
openaire   +1 more source

TRPC1 expression and distribution in rat hearts

open access: yesEuropean Journal of Histochemistry, 2009
Transient receptor potential canonical (TRPC) proteins have been identified as a family of plasma membrane calcium-permeable channels. TRPC proteins can be activated by various stimuli and act as cellular sensors in mammals.
W. Niu   +6 more
doaj   +1 more source

Identification of transient receptor potential channels in human atrial myocytes [PDF]

open access: yes, 2011
In Hong Kong Medical Journal, 2011, v. 17, suppl. 1, p. 68, abstract no. 115published_or_final_versionThe 16th Medical Resarch Conference (MRC), The University of Hong Kong, Hong Kong, China, 22 January 2011. In Hong Kong Medical Journal, 2011, v.
Lau, CP   +4 more
core  

Functions of TRPs in retinal tissue in physiological and pathological conditions

open access: yesFrontiers in Molecular Neuroscience
The Transient Receptor Potential (TRP) constitutes a family of channels subdivided into seven subfamilies: Ankyrin (TRPA), Canonical (TRPC), Melastatin (TRPM), Mucolipin (TRPML), no-mechano-potential C (TRPN), Polycystic (TRPP), and Vanilloid (TRPV ...
Thaianne Hanah Oliveira do Nascimento   +10 more
doaj   +1 more source

Differential expression and hypoxic regulation of adenosine receptors and TRPC channels in the developing heart. [PDF]

open access: yes, 2012
Objectives: To characterize the modifications of gene expression of adenosine receptors (AR), TRPC channels, HIF-1α and iNOS during the early cardiogenesis in response to chronic hypoxia exposure. Methods: 4-day-old chick embryos were subjected in ovo to
Carrupt, M.
core  

Electrophysiological characterization of store-operated and agonist-induced Ca2+ entry pathways in endothelial cells [PDF]

open access: yes, 2018
In endothelial cells, agonist-induced Ca2+ entry takes place via the store-operated Ca2+ entry pathway and/or via channel(s) gated by second messengers. As cell stimulation leads to both a partial Ca2+ store depletion as well as the production of second ...
Antigny, Fabrice   +2 more
core  

Identification of transient receptor potential channel genes from the swimming crab, Portunus Trituberculatus, and their expression profiles under acute temperature stress

open access: yesBMC Genomics
Background Temperature is an important environment factor that is critical to the survival and growth of crustaceans. However, the mechanisms by which crustaceans detect changes in temperature are still unclear.
Yichen Qian   +5 more
doaj   +1 more source

Histamine depolarizes rat intracardiac ganglion neurons through the activation of TRPC non-selective cation channels

open access: yesHistamine depolarizes rat intracardiac ganglion neurons through the activation of TRPC non-selective cation channels
European Journal of Pharmacology.
openaire  

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