Results 91 to 100 of about 7,904 (196)
Contribution of calcium-conducting channels to the transport of zinc ions. [PDF]
, 2013 International audienceZinc (Zn) is a vital nutrient participating in a myriad of biological processes. The mechanisms controlling its transport through the plasma membrane are far from being completely understood.
Bouron, Alexandre, Oberwinkler, Johannes
core +4 more sources
Molecular Plant Pathology, Volume 27, Issue 3, March 2026.MAT loci function as bistable switches in the asexual plant‐pathogenic fungus Fusarium oxysporum, controlling population behaviour through autocrine pheromone signalling. MAT1‐1 promotes hyphal fusion and virulence while repressing germination. MAT1‐2 has opposite effects, upregulating Bar1 protease that cleaves α‐pheromone.
Stefania Vitale +6 more
wiley +1 more source
TRPC3 Channels in Cardiac Fibrosis
Frontiers in Cardiovascular Medicine, 2017 Cardiac stiffness, caused by interstitial fibrosis due to deposition of extracellular matrix proteins, is thought as a major clinical outcome of heart failure with preserved ejection fraction (HFpEF).
Takuro Numaga-Tomita +12 more
doaj +1 more source
Experimental Physiology, Volume 111, Issue 3, Page 1524-1542, 1 March 2026.Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted +11 more
wiley +1 more source
TRP Channels in Angiogenesis and Other Endothelial Functions
Frontiers in Physiology, 2018 Angiogenesis is the growth of blood vessels mediated by proliferation, migration, and spatial organization of endothelial cells. This mechanism is regulated by a balance between stimulatory and inhibitory factors.
Tarik Smani +7 more
doaj +1 more source
TRP Channels Role in Pain Associated With Neurodegenerative Diseases
Frontiers in Neuroscience, 2020 Transient receptor potential (TRP) are cation channels expressed in both non-excitable and excitable cells from diverse tissues, including heart, lung, and brain.
Milena Duitama +5 more
doaj +1 more source
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels [PDF]
, 2017 The concentration of free cytosolic Ca(2+) and the voltage across the plasma membrane are major determinants of cell function. Ca(2+)-permeable non-selective cationic channels are known to regulate these parameters but understanding of these channels ...
Appleby, HL +20 more
core +2 more sources
Advanced Science, Volume 13, Issue 1, 5 January 2026.Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2010 Background and objective Transient receptor potential canonical (TRPC) proteins, a group of Ca2+ permeable nonselective cation channels, are thought to constitute store-operated calcium channels (SOCC) and mediate store-operated calcium entry (SOCE) in ...
Qi ZHANG +6 more
doaj
The Potential Role of Calcium Channels in Pulmonary Hypertension
BioMed Research International, Volume 2026, Issue 1, 2026.Pulmonary hypertension (PH) is a severe cardiovascular syndrome characterized by progressively elevated pulmonary arterial pressure and driven pathologically by sustained vasoconstriction and irreversible vascular remodeling. Growing evidence underscores the central role of calcium ion (Ca2+) signaling networks in PH pathogenesis, which dynamically ...
Ping Wu +5 more
wiley +1 more source