Results 111 to 120 of about 2,132 (150)

TRP Channels in Skin Cancer: Focus on Malignant Melanoma. [PDF]

Int J Mol Sci
Twardak D, Havryliuk V, Gagat M.
europepmc   +1 more source

TRPM2: a pivotal player in tumor progression and a promising therapeutic target. [PDF]

Cancer Cell Int
Chen Z, Wu Z, Xu T, Yu F, Wang D.
europepmc   +1 more source

Hyperosmotic Stress Promotes the Nuclear Translocation of TFEB in Tubular Epithelial Cells Depending on Intracellular Ca²⁺ Signals via TRPML Channels. [PDF]

Cell Mol Bioeng
Miyano T, Suzuki A, Konta H, Sakamoto N.
europepmc   +1 more source

Forty sites of TRP channel regulation. [PDF]

Curr Opin Chem Biol
Talyzina IA, Nadezhdin KD, Sobolevsky AI.   +2 more
europepmc   +1 more source

Calcium signaling in microglial immune functions: current understanding and implications for disease. [PDF]

Curr Opin Immunol
Lifton AR, DeMeulenaere KE, Prakriya M.
europepmc   +1 more source

Bioelectrical Regulation of Vascular Endothelial Function in Atherosclerosis. [PDF]

Biomolecules
Custodio JM, Liu JJ, Zhang L, Hong L.
europepmc   +1 more source

Organelle biology: emerging themes and future directions. [PDF]

Cell Res
Li S, Ge L.
europepmc   +1 more source

Opening the TRPML Gates [PDF]

Chemistry and Biology, 2010
The intracellular TRPML channels have multiple biological roles, but the physiological stimuli that open them remained unknown. In a previous issue of Chemistry & Biology, Grimm et al. report a high-throughput chemical screen that identified a plethora of selective activators of TRPML3 that should open the way to fully characterize these channels and ...
Shmuel Muallem
exaly   +4 more sources

Drosophila TRPML Is Required for TORC1 Activation [PDF]

Current Biology, 2012
Loss-of-function mutations in TRPML1 (transient receptor potential mucolipin 1) cause the lysosomal storage disorder, mucolipidosis type IV (MLIV). Here, we report that flies lacking the TRPML1 homolog displayed incomplete autophagy and reduced viability during the pupal period--a phase when animals rely on autophagy for nutrients.
Craig Montell, Kartik Venkatachalam, Ching On Wong   +2 more
exaly   +5 more sources

TRPML cation channels regulate the specialized lysosomal compartment of vertebrate B-lymphocytes

European Journal of Cell Biology, 2006
B-lymphocytes possess a specialized lysosomal compartment, the regulated transformation of which has been implicated in B-cell antigen presentation. Members of the mucolipin (TRPML) family of cation channels have been implicated in regulated vesicular transport in several tissues, but a role for TRPML function in lymphocyte vesicular transport ...
Andrew M Scharenberg, Sharon Matthews
exaly   +5 more sources