Targeting Sequence and Function-Dependence of Subcellular Localization of Transient Receptor Potential Mucolipin Channels and Characterization of Engineered Molecule Probes For Detecting Lysosomal Calcium Release [PDF]
Both TRPML1 and TRPML3 are members of the mucolipin subfamily of Transient Receptor Potential (TRP) channels. They have been implicated in endolysosomal functions such as divalent cation release, luminal pH regulation, autophagy and vesicle trafficking ...
Xiong, Jian
core +1 more source
On the putative role of transient receptor potential cation channels in asthma
The mammalian transient receptor potential (TRP) superfamily consists of 28 mammalian TRP cation channels, which can be subdivided into six main subfamilies: the TRPC ('Canonical'), TRPV ('Vanilloid'), TRPM ('Melastatin'), TRPP ('Polycystin'), TRPML ...
Vennekens, Rudi +5 more
core +1 more source
Structural studies of TRPML2 channels
Ion channels are fundamental and essential molecular machineries located in the membranes of diverse organelles, crucial for maintaining normal cellular function in response to various stimuli.
Park, Sunjae
core +1 more source
Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains
Different membrane microdomain compositions provide unique environments that can regulate signaling receptor function. We identify microdomains on the endosome membrane of Drosophila endosomes, enriched in lipid-raft or clathrin/ESCRT-0, which are ...
Shimizu, Hideyuki +3 more
core +1 more source
Cross-Family Mechanistic Analysis of Plant Alkaloids Against Neglected Arboviruses and Related RNA Viruses. [PDF]
Régis M +4 more
europepmc +1 more source
Obinutuzumab induces lysosomal destabilization via sphingomyelin-dependent inhibition of TRPML2. [PDF]
Oh J +6 more
europepmc +1 more source
TRP Channels from Sensory Coding to Physiology. [PDF]
Atif M, Lee Y.
europepmc +1 more source
Insights Into Aggregation-Delayed Phenotype of Dictyostelium discoideum. [PDF]
Alamer SA.
europepmc +1 more source
Contradictory Effects on Hepatocytes in ASMD. [PDF]
Sysoev M +3 more
europepmc +1 more source
Integrative screening of plant volatiles through transient receptor potential channel docking, olfactometry, and field validation in Bemisia tabaci. [PDF]
Paschapur AU +5 more
europepmc +1 more source

