Results 41 to 50 of about 4,897 (216)
Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion. [PDF]
, 2013 Serine recombinases are often tightly controlled by elaborate, topologically-defined, nucleoprotein complexes. Hin is a member of the DNA invertase subclass of serine recombinases that are regulated by a remote recombinational enhancer element containing
Chang, Yong +4 more
core +1 more source
PLoS ONE, 2023 The telomere resolvase, TelA, forms the hairpin telomeres of the linear chromosome of Agrobacterium tumefaciens in a process referred to as telomere resolution.
Mahrokh Balouchi +3 more
doaj +1 more source
Microorganisms, 2022 Eggerthella lenta is an anaerobic, high GC, Gram-positive bacillus commonly found in the human digestive tract that belongs to the class Coriobacteriia of the phylum Actinobacteria.
Colin Buttimer +5 more
doaj +1 more source
Mechanistic modelling of a recombinase-based two-input temporal logic gate [PDF]
, 2017 Site-specific recombinases (SSRs) mediate efficient manipulation of DNA sequences in vitro and in vivo. In particular, serine integrases have been identified as highly effective tools for facilitating DNA inversion, enabling the design of genetic ...
Bates, Declan +3 more
core +1 more source
Study of VIPER and TATE in kinetoplastids and the evolution of tyrosine recombinase retrotransposons [PDF]
Mobile DNA, 2019 Kinetoplastids are a flagellated group of protists, including some parasites, such as Trypanosoma and Leishmania species, that can cause diseases in humans and other animals. The genomes of these species enclose a fraction of retrotransposons including VIPER and TATE, two poorly studied transposable elements that encode a tyrosine recombinase (YR) and ...
Yasmin Carla Ribeiro +6 more
openaire +3 more sources
The unconventional Xer recombination machinery of Streptococci/Lactococci.
PLoS Genetics, 2007 Homologous recombination between circular sister chromosomes during DNA replication in bacteria can generate chromosome dimers that must be resolved into monomers prior to cell division.
Pascal Le Bourgeois +8 more
doaj +1 more source
Dual recombinase action in the normal and neoplastic mammary gland epithelium
Scientific Reports, 2021 We developed a transgenic mouse line that expresses the codon-optimized Flp recombinase under the control of the MMTV promoter in luminal epithelial cells of the mammary gland.
Patrick D. Rädler +9 more
doaj +1 more source
Nucleic Acids Research, 2023 Abstract Tyrosine-type site-specific recombinases (Y-SSRs) are versatile tools for genome engineering due to their ability to mediate excision, integration, inversion and exchange of genomic DNA with single nucleotide precision. The ever-increasing need for sophisticated genome engineering is driving efforts to identify novel SSR systems
Milica Jelicic +7 more
openaire +3 more sources
Fast growth conditions uncouple the final stages of chromosome segregation and cell division in Escherichia coli. [PDF]
PLoS Genetics, 2017 Homologous recombination between the circular chromosomes of bacteria can generate chromosome dimers. They are resolved by a recombination event at a specific site in the replication terminus of chromosomes, dif, by dedicated tyrosine recombinases.
Elisa Galli +4 more
doaj +1 more source
Integrative and Conjugative Elements (ICEs): What They Do and How They Work [PDF]
, 2015 Horizontal gene transfer plays a major role in microbial evolution, allowing microbes to acquire new genes and phenotypes. Integrative and conjugative elements (ICEs, a.k.a.
Grossman, Alan D. +3 more
core +1 more source