Results 91 to 100 of about 24,862 (198)

Bacterial Expression of Gene‐Encoding DNA Origami Structures

open access: yesSmall Structures, Volume 7, Issue 2, February 2026.
Bacterial targeting via programmable DNA origami, varying in rigidity and compactness is unexplored. In transformation assays, origami reduces transformation efficiency compared to single‐stranded scaffolds. Structural features and surface modifications, however, improve transformation outcomes.
Verena Dobretzberger   +7 more
wiley   +1 more source

Tailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics

open access: yesAdvanced Materials, Volume 38, Issue 1, 2 January 2026.
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding   +11 more
wiley   +1 more source

The Host Cell Metabolite Inositol Hexakisphosphate Promotes Efficient Endogenous HIV-1 Reverse Transcription by Stabilizing the Viral Capsid

open access: yesmBio, 2020
A defining activity of retroviruses is reverse transcription, the process by which the viral genomic RNA is converted into the double-stranded DNA required for virus replication.
Jordan Jennings   +4 more
doaj   +1 more source

Osmotic pressure: resisting or promoting DNA ejection from phage [PDF]

open access: yes, 2008
Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the course of ejection.
Castelnovo, Martin   +4 more
core   +3 more sources

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

open access: yesMedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan   +14 more
wiley   +1 more source

Intracytoplasmic Uncoated Capsids of Human Cytomegalovirus

open access: yesThe Tohoku Journal of Experimental Medicine, 1976
It has been generally accepted that capsids found in the cytoplasm of infected fibroblasts by adapted strain human cytomegalovirus (CMV) have bristle-like surface coating on them. This coating was said to be one of the important differences of CMV from herpes simplex virus.
A, Kimura, T, Tamura, T, Nakao
openaire   +2 more sources

EPS8 facilitates uncoating of influenza A virus [PDF]

open access: yesCell Reports, 2019
SUMMARYAll viruses balance interactions between cellular machinery co-opted to support replication and host factors deployed to halt the infection. We used gene correlation analysis to perform an unbiased screen for host factors involved in influenza A virus (FLUAV) infection.
Larson, Gloria P.   +9 more
openaire   +3 more sources

Structure, Function and Dynamics in Adenovirus Maturation

open access: yesViruses, 2014
Here we review the current knowledge on maturation of adenovirus, a non-enveloped icosahedral eukaryotic virus. The adenovirus dsDNA genome fills the capsid in complex with a large amount of histone-like viral proteins, forming the core.
Walter F. Mangel, Carmen San Martín
doaj   +1 more source

Severe congenital microcephaly with AP4M1 mutation, a case report [PDF]

open access: yes, 2017
Background: Autosomal recessive defects of either the B1, E1, M1 or S1 subunit of the Adaptor Protein complex-4 (AP4) are characterized by developmental delay, severe intellectual disability, spasticity, and occasionally mild to moderate microcephaly of ...
Abramowicz, Marc   +6 more
core   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

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