Results 81 to 90 of about 24,862 (198)

Unravelling Electronic Structure and Molecular Vibrations of Proteins in Virus Using Novel Correlated Plasmon‐Enhanced Raman Spectroscopy With Machine Learning

open access: yesSmall, Volume 22, Issue 14, 6 March 2026.
A novel, non‐destructive, stable, direct technique, named correlated plasmon‐enhanced Raman spectroscopy (CP‐ERS), which is based on a newly‐developed highly oriented single crystalline gold quantum dots (HOSG‐QDs) chip, is developed to measure and quantify molecular vibrations and electronic structure of analytes.
Vashu Kamboj   +7 more
wiley   +1 more source

Stability of Norwalk virus capsid protein interfaces evaluated by in-silico nanoindentation

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Norwalk virus causes severe gastroenteritis for which there is currently no specific anti-viral therapy. A stage of the infection process is uncoating of the protein capsid to expose the viral genome and allow for viral replication.
Kevin J Boyd   +3 more
doaj   +1 more source

Microtubules in Influenza Virus Entry and Egress

open access: yesViruses, 2020
Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs.
Caitlin Simpson, Yohei Yamauchi
doaj   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Unraveling the Motions behind Enterovirus 71 Uncoating [PDF]

open access: yesBiophysical Journal, 2018
Enterovirus 71 can be a severe pathogen in small children and immunocompromised adults. Virus uncoating is a critical step in the infection of the host cell; however, the mechanisms that control this process remain poorly understood. We applied normal mode analysis and perturbation response scanning to several complexes of the virus capsid and present ...
Ross, Caroline Jane   +3 more
openaire   +4 more sources

THE ROLE OF THE NEONATAL FC RECEPTOR IN THE UNCOATING OF ECHOVIRUSES AND COXSACKIEVIRUS A9

open access: yesВопросы вирусологии, 2019
The aim of this study was to determine the role of the human neonatal receptor for the Fc fragment of IgG (hFcRn) as a common uncoating cellular receptor for echoviruses and coxsackievirus A9 during infection of human rhabdomyosarcoma (RD) cells ...
P. S. Usoltseva   +4 more
doaj   +1 more source

An HIV-1 capsid binding protein TRIM11 accelerates viral uncoating [PDF]

open access: yes, 2016
Additional file 1: Figure S1. TRIM11 expression levels in different cells. HEK293, THP-1, PMA treated THP-1 cells and Jurkat cells were lysed with cell lysis buffer.
Binlian Sun   +4 more
core   +2 more sources

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang   +14 more
wiley   +1 more source

Protease-Dependent Uncoating of a Complex Retrovirus [PDF]

open access: yesJournal of Virology, 2005
ABSTRACT Although retrovirus egress and budding have been partly unraveled, little is known about early stages of the replication cycle. In particular, retroviral uncoating, a process during which incoming retroviral cores are altered to allow the integration of the viral genome into host chromosomes, is poorly understood.
Lehmann-Che, J.   +7 more
openaire   +3 more sources

A single point mutation in precursor protein VI doubles the mechanical strength of human adenovirus [PDF]

open access: yes, 2017
Viruses are extensively studied as vectors for vaccine applications and gene therapies. For these applications, understanding the material properties of viruses is crucial for creating optimal functionality.
Nemerow, Glen R   +3 more
core   +2 more sources

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