Results 51 to 60 of about 29,177 (237)
Targeting Unconventional T Cells for Vaccination against Tuberculosis. [PDF]
Am J Respir Cell Mol Biol, 2020 Wilkinson KA, Cerrone M.
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Special Issue “Gamma Delta T Cells in Immune Response against Viruses”
Viruses, 2022 γδ T cells are members of ‘unconventional’ T cells that combine the properties of adaptive T lymphocytes and innate cells such as NK cells [...]
Eric Champagne
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The multisensory regulation of unconventional T cell homeostasis
Seminars in Immunology, 2022 Unconventional T cells typically group γδ T cells, invariant Natural Killer T cells (NKT) and Mucosal Associated Invariant T (MAIT) cells. With their pre-activated status and biased tropism for non-lymphoid organs, they provide a rapid (innate-like) and efficient first line of defense against pathogens at strategical barrier sites, while they can also ...
Julie, Darrigues +3 more
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An unconventional view of COVID-19 T cell immunity [PDF]
Journal of Experimental Medicine, 2020 In this issue of JEM, Jouan et al. (https://doi.org/10.1084/jem.20200872) report the activation and skewed function of unconventional T cells in severe COVID-19 patients. This may reflect a role in COVID-19 immunity or pathogenesis and potentially identifies new therapeutic targets for this disease.
Koay, Hui-Fern +2 more
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UcTCRdb: An unconventional T cell receptor sequence database with online analysis functions
Frontiers in Immunology, 2023 Unlike conventional major histocompatibility complex (MHC) class I and II molecules reactive T cells, the unconventional T cell subpopulations recognize various non-polymorphic antigen-presenting molecules and are typically characterized by simplified ...
Yunsheng Dou, Shiwen Shan, Jian Zhang
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Commensal bacteria maintain a Qa-1b-restricted unconventional CD8+ T population in gut epithelium
eLife, 2023 Intestinal intraepithelial lymphocytes (IELs) are characterized by an unusual phenotype and developmental pathway, yet their specific ligands and functions remain largely unknown. Here by analysis of QFL T cells, a population of CD8+ T cells critical for
Jian Guan +5 more
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Where do MAIT cells fit in the family of unconventional T cells?
PLoS Biology, 2009 Mucosal-associated invariant T cells are newly identified subpopulation of T cells. A new study highlights their developmental pathway and functional features that allow these cells to assume a unique position in the family of unconventional T cells.
Laurent Gapin
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Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Frontiers in Immunology, 2021 Mucosal surfaces, as a first barrier with the environment are especially susceptible to damage from both pathogens and physical trauma. Thus, these sites require tightly regulated repair programs to maintain barrier function in the face of such insults ...
Joshua R. Cox +4 more
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Frontiers in Immunology, 2023 The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce +3 more
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