Results 51 to 60 of about 102,674 (250)
Frontiers in Immunology, 2021 The development and differentiation of T cells represents a long and highly coordinated, yet flexible at some points, pathway, along which the sequential and dynamic expressions of different transcriptional factors play prominent roles at multiple steps.
Zhong-Yan Cheng +4 more
doaj +1 more source
An unconventional view of COVID-19 T cell immunity [PDF]
Journal of Experimental Medicine, 2020 In this issue of JEM, Jouan et al. (https://doi.org/10.1084/jem.20200872) report the activation and skewed function of unconventional T cells in severe COVID-19 patients. This may reflect a role in COVID-19 immunity or pathogenesis and potentially identifies new therapeutic targets for this disease.
Koay, Hui-Fern +2 more
openaire +3 more sources
Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation [PDF]
, 2015 Despite effective anti-viral therapies, cytomegalovirus (CMV) is still associated with direct (CMV disease) and indirect effects (rejection and poor graft survival) in kidney transplant recipients.
Jean-François eMoreau +5 more
core +2 more sources
Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies
EBioMedicine, 2022 Summary: Background: Non-protein antigen classes can be presented to T cells by near-monomorphic antigen-presenting molecules such as CD1, MR1, and butyrophilin 3A1.
Anele Gela +22 more
doaj +1 more source
Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases
Life Science Alliance, 2022 We describe an improved method for the high-dimensional flow cytometry analysis of conventional and rare unconventional T cells infiltrating tumor liver metastases.
Cristina Faccani +17 more
doaj +1 more source
An Unconventional View of T Cell Reconstitution After Allogeneic Hematopoietic Cell Transplantation
Frontiers in Oncology, 2021 Allogeneic hematopoietic cell transplantation (allo-HCT) is performed as curative-intent therapy for hematologic malignancies and non-malignant hematologic, immunological and metabolic disorders, however, its broader implementation is limited by high ...
Hana Andrlová +5 more
doaj +1 more source
T Cells in Osteoarthritis: Alterations and Beyond [PDF]
, 2017 Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease, reports increasingly suggest that it is inflammatory, at least in certain patients.
Guang-hua Lei +3 more
core +1 more source
Casting a wider net: Immunosurveillance by nonclassical MHC molecules.
PLoS Pathogens, 2019 Most studies of T lymphocytes focus on recognition of classical major histocompatibility complex (MHC) class I or II molecules presenting oligopeptides, yet there are numerous variations and exceptions of biological significance based on recognition of a
M Patricia D'Souza +24 more
doaj +1 more source
KLHL12 promotes non-lysine ubiquitination of the dopamine receptors D-4.2 and D-4.4, but not of the ADHD-associated D-4.7 variant [PDF]
, 2015 Dopamine D-4 Receptor Polymorphism : The dopamine D-4 receptor has an important polymorphism in its third intracellular loop that is intensively studied and has been associated with several abnormal conditions, among others, attention deficit ...
Lintermans, Béatrice +3 more
core +4 more sources
STAR Protocols, 2022 Summary: Cytotoxic T lymphocytes and natural killer (NK) cells are key effector cells in immune defenses against intracellular pathogens and cancer. In human blood, effector T and NK cytotoxic cells comprise a diverse and relatively rare group of cells ...
Gisele V. Baracho +5 more
doaj +1 more source