Uncoupling Protein 1 Promotes Nile Tilapia Resistance to Acute Cold Stress by Regulating Liver Metabolism [PDF]
MetabolitesBackground: Low temperature stress is a major environmental challenge affecting the growth, metabolism, and survival of many aquaculture species, including Nile tilapia (Oreochromis niloticus).
Meiqing Li +8 more
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Relationship between uncoupling protein 1 (UCP1) levels and psoriasis. [PDF]
Turk J Med SciBackground/aim: Psoriasis is an autoimmune, chronic and common skin disease. Comorbidities also increase the mortality risk of the disease. The aim of this study is to investigate the changes in UCP1 levels in psoriasis patients and to evaluate their possible role in the pathogenesis of the disease, focusing on disease severity (Psoriasis Area and ...
Akyürek F +2 more
europepmc +3 more sources
Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. [PDF]
Sci Rep, 2019 The number of brown adipocytes residing within murine white fat depots (brite adipocytes) varies a lot by depot, strain and physiological condition. Several endocrine fibroblast growth factors are implicated in the regulation of brite adipocyte abundance.
Westphal S +5 more
europepmc +2 more sources
Impact of the Uncoupling Protein 1 on Cardiovascular Risk in Patients with Rheumatoid Arthritis [PDF]
Cells, 2021 Adiposity is strongly associated with cardiovascular (CV) morbidity. Uncoupling protein 1 (UCP1) increases energy expenditure in adipocytes and may counteract adiposity.
Lovisa I. Lyngfelt +9 more
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Uncoupling Protein-1 (UCP1) in the Adult Horse: Correlations with Body Weight, Rectal Temperature and Lipid Profile [PDF]
Animals, 2021 This study aimed to evaluate the possible relationship among UCP1, body weight, rectal temperature and lipid profile in the horse. Thirty clinically healthy Italian Saddle geldings (6–10 years old) were enrolled after the informed owners’ consent.
Francesca Arfuso +4 more
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Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1 [PDF]
Laboratory Animal ResearchBackground Uncoupling protein 1 (UCP1) is a proton uncoupler located across the mitochondrial membrane generally involved in thermogenesis of brown adipose tissues.
Gi-Sue Kang +10 more
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Cell-free production and characterisation of human uncoupling protein 1–3
Biochemistry and Biophysics Reports, 2017 The uncoupling proteins (UCPs) leak protons across the inner mitochondrial membrane, thus uncoupling the proton gradient from ATP synthesis. The main known physiological role for this is heat generation by UCP1 in brown adipose tissue.
Etienne Rebuffet +3 more
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Proton conductance by human uncoupling protein 1 is inhibited by purine and pyrimidine nucleotides [PDF]
The EMBO JournalUncoupling protein 1 (UCP1, SLC25A7) is responsible for the thermogenic properties of brown adipose tissue. Upon fatty acid activation, UCP1 facilitates proton leakage, dissipating the mitochondrial proton motive force to release energy as heat.
Scott A Jones +9 more
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In silico identification of lipid-binding α helices of uncoupling protein 1. [PDF]
Biomed Rep, 2018 Uncoupling protein 1 (UCP1) located at the mitochondrial inner membrane serves an important role in adaptive non-shivering thermogenesis. Previous data has demonstrated that membrane lipids regulate the biological functions of membrane proteins. However, how mitochondrial lipids interact with UCP1 still remains elusive.
Jing Y, Niu Y, Liu C, Zen K, Li D.
europepmc +4 more sources
Ibuprofen, a direct activator of uncoupling protein 1
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022 Riccardo Cavalieri +7 more
semanticscholar +2 more sources