Results 61 to 70 of about 22,011 (155)
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.Pan‐cancer analysis reveals an inflammatory phenotype remodeling of tissue‐resident macrophages (iTRM) in the tumor microenvironment, which is associated with immunosuppression. Tissue‐resident macrophages and monocyte‐derived macrophages exhibit convergent differentiation toward a similar inflammatory phenotype. iTRM‐enriched ecosystems are associated
Weikai Wang +19 more
wiley +1 more source
Plectin as a prognostic marker in non-metastatic oral squamous cell carcinoma [PDF]
, 2014 Background: Oral squamous cell carcinoma (OSCC) is associated with a poor 5-year survival rate. In general, patients diagnosed with small tumors have a fairly good prognosis, but some small tumors have an aggressive behavior leading to early death. There
Oddveig G. Rikardsen +41 more
core +2 more sources
Cell Proliferation, Volume 59, Issue 2, February 2026.Homoharringtonine (HHT) suppresses immune evasion in acute monocytic leukaemia (AML‐M5) by attenuating the FTO/m6A/LILRB4 axis, thereby enhancing CD8+ T cell cytotoxicity. ABSTRACT Acute monocytic leukaemia, a subtype of acute myeloid leukaemia (AML), is a highly aggressive malignancy characterised by a poor prognosis, primarily due to the ability of ...
Fangfang Huang +18 more
wiley +1 more source
大腸癌の進展におけるインターロイキン8とプラスミノーゲンアクチベーターシステムとの関連 [PDF]
, 2006 浜松医科大学学位論文 医博論第413号 ...
650, 寺田, 博文
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The FASEB Journal, Volume 40, Issue 1, 15 January 2026.Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay +4 more
wiley +1 more source
Functionals defined on piecewise rigid functions: Integral representation and $\Gamma$-convergence
, 2020 We analyze integral representation and $\Gamma$-convergence properties of functionals defined on \emph{piecewise rigid functions}, i.e., functions which are piecewise affine on a Caccioppoli partition where the derivative in each component is constant ...
Friedrich, Manuel, Solombrino, Francesco
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Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, Volume 13, Issue 4, 19 January 2026.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]
, 2016 Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica +10 more
core +2 more sources
Advanced Science, Volume 13, Issue 5, 27 January 2026.A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li +13 more
wiley +1 more source
ChemBioChem, Volume 27, Issue 1, January 2026.Radiopharmaceuticals enable precise cancer diagnosis and targeted therapy by combining radioactive isotopes with carrier molecules. This review summarizes advances from 2014 to 2025, emphasizing probe design, click chemistry, novel targets, and nanodelivery systems.
Mohd Sayeed Shaikh +7 more
wiley +1 more source