Results 81 to 90 of about 22,011 (155)

Das uPAR-System: Identifizierung neuer uPAR-Interaktionspartner und ihre Relevanz beim triple-negativen Brustkrebs [PDF]

, 2016
In dieser Arbeit führte die dauerhafte Reduzierung der Proteinexpression von uPAR kombiniert mit uPA bzw. IGF-1R zu einem reduzierten Tumorverhalten in vitro und könnte einen Ansatz für eine bessere TNBC-Therapie darstellen. IGF-1R wurde als direkter Interaktionspartner von uPAR bestätigt.
openaire  

Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. [PDF]

, 2019
Asthma is a common disorder of the airways characterized by airway inflammation and by decline in lung function and airway remodeling in a subset of asthmatics.
Broide, David H, Hur, Gyu Young
core  

Numerical study of cancer cell invasion dynamics using adaptive mesh refinement: the urokinase model

, 2014
In the present work we investigate the chemotactically and proteolytically driven tissue invasion by cancer cells. The model employed is a system of advection-reaction-diffusion equations that features the role of the serine protease urokinase-type ...
Hellmann, Nadja, Katuchova, Jana, Kolbe, Niklas, Lukacova-Medvidova, Maria, Sfakianakis, Nikolaos   +4 more
core  

The role of suPAR and related proteins in kidney, heart diseases, and diabetes. [PDF]

J Clin Invest
Reiser J, Hayek SS, Sever S.
europepmc   +1 more source

Anti-uPAR CAR T cells reverse and prevent aging-associated defects in intestinal regeneration and fitness. [PDF]

Nat Aging
Eskiocak O, Gewolb J, Shah V, Rouse JA, Chowdhury S, Akyildiz EO, Fernández-Maestre I, Boyer JA, Filliol A, Harris AS, Utama R, Guo G, Castro-Hernández C, Nnuji-John E, Chung C, Anderson A, Flowers S, Habel J, Romesser PB, Levine RL, Lowe SW, Sadelain M, Beyaz S, Amor C.   +23 more
europepmc   +1 more source

Virus-derived serpin reduces immuno-coagulopathic damage in murine colitis by targeting the urokinase-type plasminogen activator receptor (uPAR) and complement. [PDF]

Sci Rep
Lucas AR, Monder H, Enow J, Woodrow C, Spaccarelli L, Garg A, Schlievert J, Elmadbouly N, Dupati A, Aliskevich E, Saju R, Kilbourne J, Lowe K, Hamada M, Pinteric A, Zanetti IR, Satyanarayanan RS, Gisriel S, Florsheim EB, Rahman M, Irving J, McFadden G, Kong W, Zhang L.   +23 more
europepmc   +1 more source

The Urokinase-Type Plasminogen Activator Receptor (uPAR) as a Mediator of Physiological and Pathological Processes: Potential Therapeutic Strategies. [PDF]

Cancers (Basel)
Iftikhar A, Mahmood N, Rabbani SA.
europepmc   +1 more source

[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells. [PDF]

Int J Oncol
Alapati K, Gopinath S, Malla RR, Dasari VR, Rao JS.   +4 more
europepmc   +1 more source

Interferon alpha-induced uPAR expression on monocytes as a potential source of increased soluble uPAR in patients with SLE at high risk of developing organ damage. [PDF]

Clin Exp Med
Wirestam L, Karlsson J, Welin A, Álvarez-Gómez JA, Wetterö J, Sjöwall C, Enocsson H.   +6 more
europepmc   +1 more source

Preclinical evaluation of uPAR-ICG-FVIOs for dual-mode imaging and magnetic hyperthermia therapy in pancreatic cancer. [PDF]

Front Pharmacol
Luo T, Zhang K, Wu C, Wu X, Yang H, Chen Z, Jiang F.   +6 more
europepmc   +1 more source