Results 11 to 20 of about 116,102 (224)
Uremic Toxins and Protein-Bound Therapeutics in AKI and CKD: Up-to-Date Evidence
Toxins, 2021 Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on CKD
Jia-Huang Chen, Chih-Kang Chiang
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Food-Derived Uremic Toxins in Chronic Kidney Disease [PDF]
Toxins, 2023 Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to the average population, and this is partially due to the plasma accumulation of solutes known as uremic toxins.
Mara Lauriola +4 more
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Role of Uremic Toxins in Early Vascular Ageing and Calcification
Toxins, 2021 In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused by a combination of decreased excretion secondary to reduced kidney function and increased generation secondary to aberrant expression of metabolite genes ...
Nikolaos C. Kyriakidis +4 more
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Toxins, 2020 Uremic vascular calcification (VC) commonly occurs during advanced chronic kidney disease (CKD) and significantly increases cardiovascular morbidity and mortality.
Chia-Ter Chao, Shih-Hua Lin
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Targeting Uremic Toxins to Prevent Peripheral Vascular Complications in Chronic Kidney Disease
Toxins, 2020 Chronic kidney disease (CKD) exhibits progressive kidney dysfunction and leads to disturbed homeostasis, including accumulation of uremic toxins, activated renin-angiotensin system, and increased oxidative stress and proinflammatory cytokines.
Chia-Lin Wu, Der-Cherng Tarng
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Lipid Profile Is Negatively Associated with Uremic Toxins in Patients with Kidney Failure—A Tri-National Cohort [PDF]
Toxins, 2022 Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly driven by insufficient clearance of uremic toxins. Recent investigations have questioned the accepted effects of adverse lipid profile and CV risk in uremic ...
Sam Hobson +6 more
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Expanded Haemodialysis as a Current Strategy to Remove Uremic Toxins [PDF]
Toxins, 2021 Chronic kidney disease (CKD) is characterized by the retention of solutes named uremic toxins, which strongly associate with high morbidity and mortality. Mounting evidence suggests that targeting uremic toxins and/or their pathways may decrease the risk
Paola Ciceri, Mario Cozzolino
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Uremic Toxins and Vascular Dysfunction [PDF]
Toxins, 2020 Vascular dysfunction is an essential element found in many cardiovascular pathologies and in pathologies that have a cardiovascular impact such as chronic kidney disease (CKD). Alteration of vasomotricity is due to an imbalance between the production of relaxing and contracting factors. In addition to becoming a determining factor in pathophysiological
Six, I. +7 more
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Composite Uremic Load and Physical Performance in Hemodialysis Patients: A Cross-Sectional Study [PDF]
Toxins, 2020 Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking.
Karsten Vanden Wyngaert +5 more
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Cardiotoxicity of Uremic Toxins: A Driver of Cardiorenal Syndrome
Toxins, 2018 Cardiovascular disease (CVD) is highly prevalent in the setting of chronic kidney disease (CKD). Such coexistence of CVD and CKD—the so-called “cardiorenal or renocardiac syndrome”—contributes to exponentially increased risk of ...
Suree Lekawanvijit
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