Results 21 to 30 of about 116,102 (224)
Intestinal Chelators, Sorbants, and Gut-Derived Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is a highly prevalent condition and is associated with a high comorbidity burden, polymedication, and a high mortality rate.
Solène M. Laville +5 more
doaj +2 more sources
Uremic Toxins and Atrial Fibrillation: Mechanisms and Therapeutic Implications
Toxins, 2019 Atrial fibrillation (AF) is the most prevalent arrhythmia in the general population. There is a close association between chronic kidney disease (CKD) and AF.
Fumi Yamagami +3 more
doaj +2 more sources
The Microbiome and Uremic Solutes
Toxins, 2022 Uremic retention solutes, especially the protein-bound compounds, are toxic metabolites, difficult to eliminate with progressive renal functional decline.
Nadim Zaidan, Lama Nazzal
doaj +2 more sources
Gut Microbiota and Cardiovascular Uremic Toxicities [PDF]
Toxins, 2018 Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez +4 more
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Uremic Toxins in Organ Crosstalk [PDF]
Frontiers in Medicine, 2021 Many putative uremic toxins—like indoxyl sulfate, p-cresol sulfate, kynurenic acid, uric acid, and CMPF—are organic anions. Both inter-organ and inter-organismal communication are involved.
Jerome Lowenstein, Sanjay K. Nigam
doaj +3 more sources
The Impact of CKD on Uremic Toxins and Gut Microbiota
Toxins, 2021 Numerous studies have indicated that the progression of chronic kidney disease (CKD) to end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic metabolites in blood and other metabolic compartments.
Jacek Rysz +5 more
doaj +2 more sources
Association between Dental Scores and Saliva Uremic Toxins [PDF]
Toxins, 2023 Dental health is frequently altered in patients with chronic kidney disease. We conducted a prospective study on dental health in CKD patients with a specific interest in the association between dental health issues and the accumulation of uremic toxins ...
Claire Rigothier +8 more
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Toxins, 2014 Patients with chronic kidney disease (CKD) have a higher risk of cardiovascular diseases and suffer from accelerated atherosclerosis. CKD patients are permanently exposed to uremic toxins, making them good candidates as pathogenic agents.
Marion Sallée +5 more
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Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease
Toxins, 2018 Patients with chronic kidney disease (CKD) display an elevated risk of thrombosis. Thrombosis occurs in cardiovascular events, such as venous thromboembolism, stroke, and acute coronary syndrome, and is a cause of hemodialysis vascular access dysfunction.
Tawfik Addi +2 more
doaj +2 more sources
Future of Uremic Toxin Management
ToxinsDuring the progression of chronic kidney disease (CKD), the retention of uremic toxins plays a key role in the development of uremic syndrome. Knowledge about the nature and biological impact of uremic toxins has grown exponentially over the past decades.
Raymond Vanholder +3 more
doaj +4 more sources