Results 21 to 30 of about 15,787 (202)
Searching for Uremic Toxins [PDF]
Clinical Journal of the American Society of Nephrology, 2013 Summary Treatment of uremia by hemodialysis has become widespread over the last 40 years and has improved substantially over that time. However, people treated with this modality continue to suffer from multiple disabilities. Retention of organic solutes, especially those poorly removed by hemodialysis, likely contributes to ...
Mirela, Dobre +2 more
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Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression
Toxins, 2018 In chronic kidney disease (CKD), accumulation of uremic toxins is associated with an increased risk of CKD progression. Some uremic toxins result from nutrient processing by gut microbiota, yielding precursors of uremic toxins or uremic toxins themselves,
Esmeralda Castillo-Rodriguez +13 more
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Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients. [PDF]
PLoS ONE, 2017 Numerous outcome studies and interventional trials in hemodialysis (HD) patients are based on uremic toxin concentrations determined at one single or a limited number of time points.
Sunny Eloot +7 more
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Expanded Haemodialysis as a Current Strategy to Remove Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is characterized by the retention of solutes named uremic toxins, which strongly associate with high morbidity and mortality. Mounting evidence suggests that targeting uremic toxins and/or their pathways may decrease the risk
Paola Ciceri, Mario Cozzolino
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Heliyon, 2021 One third of the patients with chronic kidney disease (CKD) develop cognitive impairment, which is also an independent risk factor for mortality. However, the concise mechanism of cerebro-renal interaction has not been clarified.
Kimio Watanabe +6 more
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Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells
Toxins, 2014 The risk of myopathy and rhabdomyolysis is considerably increased in statin users with end-stage renal failure (ESRF). Uremic toxins, which accumulate in patients with ESRF, exert cytotoxic effects that are mediated by various mechanisms.
Hitoshi Uchiyama +11 more
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Targeting Uremic Toxins to Prevent Peripheral Vascular Complications in Chronic Kidney Disease
Toxins, 2020 Chronic kidney disease (CKD) exhibits progressive kidney dysfunction and leads to disturbed homeostasis, including accumulation of uremic toxins, activated renin-angiotensin system, and increased oxidative stress and proinflammatory cytokines.
Chia-Lin Wu, Der-Cherng Tarng
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Intestinal Chelators, Sorbants, and Gut-Derived Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is a highly prevalent condition and is associated with a high comorbidity burden, polymedication, and a high mortality rate.
Solène M. Laville +5 more
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Gut Microbiota and Cardiovascular Uremic Toxicities
Toxins, 2018 Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez +4 more
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Composite Uremic Load and Physical Performance in Hemodialysis Patients: A Cross-Sectional Study
Toxins, 2020 Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking.
Karsten Vanden Wyngaert +5 more
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