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Uremic Toxins and Cardiovascular System [PDF]
Cardiology Clinics, 2021 When chronic kidney disease develops, the capacity of the kidneys to clear metabolic waste products from the body is gradually lost. This process results in the retention of a large array of compounds affecting biochemical and biological functions (uremic toxins), of which several can cause cardiovascular damage.
Valkenburg, Sophie +2 more
openaire +3 more sources
Food-Derived Uremic Toxins in Chronic Kidney Disease
Toxins, 2023 Patients with chronic kidney disease (CKD) have a higher cardiovascular risk compared to the average population, and this is partially due to the plasma accumulation of solutes known as uremic toxins.
Mara Lauriola +4 more
doaj +1 more source
The Interplay between Uremic Toxins and Albumin, Membrane Transporters and Drug Interaction
Toxins, 2022 Uremic toxins are a heterogeneous group of molecules that accumulate in the body due to the progression of chronic kidney disease (CKD). These toxins are associated with kidney dysfunction and the development of comorbidities in patients with CKD, being ...
Regiane Stafim da Cunha +6 more
doaj +1 more source
Carbamoylated nail proteins as assessed by near-infrared analysis are associated with load of uremic toxins and mortality in hemodialysis patients [PDF]
, 2020 Carbamoylation is an important risk factor for accelerated atherogenesis and mortality in patients undergoing hemodialysis (HD). We intended to explore whether carbamoylation as assessed by near-infrared (NIR) analysis of nail proteins is associated with
De Bruyne, Sander +7 more
core +1 more source
Toxins, 2022 Patients with kidney failure (KF) have a high incidence of cardiovascular (CV) disease, partly driven by insufficient clearance of uremic toxins. Recent investigations have questioned the accepted effects of adverse lipid profile and CV risk in uremic ...
Sam Hobson +6 more
doaj +1 more source
Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression
Toxins, 2018 In chronic kidney disease (CKD), accumulation of uremic toxins is associated with an increased risk of CKD progression. Some uremic toxins result from nutrient processing by gut microbiota, yielding precursors of uremic toxins or uremic toxins themselves,
Esmeralda Castillo-Rodriguez +13 more
doaj +1 more source
Binding of bromocresol green and bromocresol purple to albumin in hemodialysis patients [PDF]
, 2017 BACKGROUND: Colorimetric albumin assays based on binding to bromocresol purple (BCP) and bromocresol green (BCG) yield different results in chronic kidney disease. Altered dye binding of carbamylated albumin has been suggested as a cause.
Delanghe, Joris +8 more
core +1 more source
Expanded Haemodialysis as a Current Strategy to Remove Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is characterized by the retention of solutes named uremic toxins, which strongly associate with high morbidity and mortality. Mounting evidence suggests that targeting uremic toxins and/or their pathways may decrease the risk
Paola Ciceri, Mario Cozzolino
doaj +1 more source
Heliyon, 2021 One third of the patients with chronic kidney disease (CKD) develop cognitive impairment, which is also an independent risk factor for mortality. However, the concise mechanism of cerebro-renal interaction has not been clarified.
Kimio Watanabe +6 more
doaj +1 more source
Changes in the Conformational State of Hemoglobin in Hemodialysed Patients with Chronic Renal Failure [PDF]
, 2015 The aim of this study was to evaluate the properties of internal components of erythrocytes in chronic renal failure (CRF) patients undergoing hemodialysis (HD) in comparison to control subjects.
Gwozdzinski, Krzysztof +1 more
core +7 more sources