Serum levels and removal by haemodialysis and haemodiafiltration of tryptophan-derived uremic toxins in ESKD patients [PDF]
, 2020 Tryptophan is an essential dietary amino acid that originates uremic toxins that contribute to end-stage kidney disease (ESKD) patient outcomes.
Adoberg, A +15 more
core +1 more source
Searching for Uremic Toxins [PDF]
Clinical Journal of the American Society of Nephrology, 2013 Summary Treatment of uremia by hemodialysis has become widespread over the last 40 years and has improved substantially over that time. However, people treated with this modality continue to suffer from multiple disabilities. Retention of organic solutes, especially those poorly removed by hemodialysis, likely contributes to ...
Mirela, Dobre +2 more
openaire +2 more sources
Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells
Toxins, 2014 The risk of myopathy and rhabdomyolysis is considerably increased in statin users with end-stage renal failure (ESRF). Uremic toxins, which accumulate in patients with ESRF, exert cytotoxic effects that are mediated by various mechanisms.
Hitoshi Uchiyama +11 more
doaj +1 more source
Targeting Uremic Toxins to Prevent Peripheral Vascular Complications in Chronic Kidney Disease
Toxins, 2020 Chronic kidney disease (CKD) exhibits progressive kidney dysfunction and leads to disturbed homeostasis, including accumulation of uremic toxins, activated renin-angiotensin system, and increased oxidative stress and proinflammatory cytokines.
Chia-Lin Wu, Der-Cherng Tarng
doaj +1 more source
Dinucleoside polyphosphates : newly detected uraemic compounds with an impact on leucocyte oxidative burst [PDF]
, 2009 Background. Dinucleoside polyphosphates (NpnN) have pathophysiologic roles in cardiovascular disease and are newly detected uraemic retention solutes. They were retrieved in human plasma, tissues and cells.
Dhondt, Annemieke +5 more
core +1 more source
Intestinal Chelators, Sorbants, and Gut-Derived Uremic Toxins
Toxins, 2021 Chronic kidney disease (CKD) is a highly prevalent condition and is associated with a high comorbidity burden, polymedication, and a high mortality rate.
Solène M. Laville +5 more
doaj +1 more source
Single needle hemodialysis : is the past the future? [PDF]
, 2020 Whereas the usual way to gain access to the vascular bed for hemodialysis is by inserting two needles, an alternative option based on the introduction of only one needle has been available for several decades.
Vanholder, Raymond
core +2 more sources
Gut Microbiota and Cardiovascular Uremic Toxicities
Toxins, 2018 Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez +4 more
doaj +1 more source
Composite Uremic Load and Physical Performance in Hemodialysis Patients: A Cross-Sectional Study
Toxins, 2020 Impaired physical performance is common in patients on hemodialysis (HD) and is associated with poor prognosis. A patient relevant marker of adequacy of dialysis is lacking.
Karsten Vanden Wyngaert +5 more
doaj +1 more source
Uremic toxins. Back to the future
Počki, 2021 In the review, the author returns to the topic of uremia and uremic toxins, their importance for practitioners in the treatment using renal replacement therapies, gives a modern look at their classification, place during the onset and development of ...
I.L. Kuchma
doaj +1 more source