Results 31 to 40 of about 116,102 (224)
A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients [PDF]
Toxins, 2019 Hydrophobic uremic toxins accumulate in patients with chronic kidney disease, contributing to a highly increased cardiovascular risk. The clearance of these uremic toxins using current hemodialysis techniques is limited due to their hydrophobicity and ...
Marieke Sternkopf +12 more
doaj +2 more sources
Uremic Toxins and Cardiovascular System [PDF]
Cardiology Clinics, 2021 When chronic kidney disease develops, the capacity of the kidneys to clear metabolic waste products from the body is gradually lost. This process results in the retention of a large array of compounds affecting biochemical and biological functions (uremic toxins), of which several can cause cardiovascular damage.
Valkenburg, Sophie +2 more
openaire +3 more sources
The removal of uremic toxins [PDF]
Kidney International, 2000 Three major groups of uremic solutes can be characterized: the small water-soluble compounds, the middle molecules, and the protein-bound compounds. Whereas small water-soluble compounds are quite easily removed by conventional hemodialysis, this is not the case for many other molecules with different physicochemical characteristics.
Dhondt, Annemieke +3 more
openaire +2 more sources
Searching for Uremic Toxins [PDF]
Clinical Journal of the American Society of Nephrology, 2013 Summary Treatment of uremia by hemodialysis has become widespread over the last 40 years and has improved substantially over that time. However, people treated with this modality continue to suffer from multiple disabilities. Retention of organic solutes, especially those poorly removed by hemodialysis, likely contributes to ...
Mirela, Dobre +2 more
openaire +2 more sources
Impact of Altered Intestinal Microbiota on Chronic Kidney Disease Progression
Toxins, 2018 In chronic kidney disease (CKD), accumulation of uremic toxins is associated with an increased risk of CKD progression. Some uremic toxins result from nutrient processing by gut microbiota, yielding precursors of uremic toxins or uremic toxins themselves,
Esmeralda Castillo-Rodriguez +13 more
doaj +1 more source
Uremic Toxins: An Alarming Danger Concerning the Cardiovascular System
Frontiers in Physiology, 2021 The kidneys and heart share functions with the common goal of maintaining homeostasis. When kidney injury occurs, many compounds, the so-called “uremic retention solutes” or “uremic toxins,” accumulate in the circulation targeting other tissues.
Carlos Alexandre Falconi +6 more
doaj +1 more source
Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients. [PDF]
PLoS ONE, 2017 Numerous outcome studies and interventional trials in hemodialysis (HD) patients are based on uremic toxin concentrations determined at one single or a limited number of time points.
Sunny Eloot +7 more
doaj +1 more source
'Uremic toxin' section in the journal Toxins : a powerful tool to bundle and advance knowledge on uremia [PDF]
, 2017 In the journal Toxins, a new section has been added to those already included, which will be specifically devoted to uremic toxins.[...
Vanholder, Raymond, Raymond Vanholder
core +1 more source
Inflammatory Cytokines as Uremic Toxins: “Ni Son Todos Los Que Estan, Ni Estan Todos Los Que Son” [PDF]
, 2017 Chronic kidney disease is among the fastest growing causes of death worldwide. An increased risk of all-cause and cardiovascular death is thought to depend on the accumulation of uremic toxins when glomerular filtration rate falls.
Fernandez-Fernandez, Beatriz +15 more
core +1 more source
, 2021 The retention of uremic toxins and their pathological effects occurs in the advanced phases of chronic kidney disease (CKD), mainly in stage 5, when the implementation of conventional thrice-weekly hemodialysis is the prevalent and life-saving treatment.
Adamasco Cupisti +5 more
core +1 more source