Results 101 to 110 of about 4,757 (208)

PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles

Journal of Nanobiotechnology, 2022
Highlights 1. CuONPs disturb mitochondrial dynamics and trigger mitophagy in vascular endothelial cells and mouse blood vessel. 2. PINK1/TAX1BP1-mediated mitophagy regulates the removal of excessive ROS and aberrant mitochondria in CuONPs-treated ...
Yinzhen Fan, Zhenli Cheng, Lejiao Mao, Ge Xu, Na Li, Mengling Zhang, Ping Weng, Lijun Zheng, Xiaomei Dong, Siyao Hu, Bin Wang, Xia Qin, Xuejun Jiang, Chengzhi Chen, Jun Zhang, Zhen Zou   +15 more
doaj   +1 more source

Effects of pomegranate juice in circulating parameters, cytokines, and oxidative stress markers in endurance-based athletes: A randomized controlled trial [PDF]

, 2016
Objective: The aim of the present study was to assess the effects of pomegranate juice on the level of oxidative stress in the blood of endurance-based athletes.
Funes, Lorena, Fuster-Muñoz, Encarnación, Martínez-Peinado, Pascual, Roche, Enrique, Sempere Ortells, José Miguel, Vicente Salar, Nestor   +5 more
core   +2 more sources

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats

Cardiovascular Diabetology, 2017
Background Emerging evidence suggests that specific (poly)phenols may constitute new preventative strategies to counteract cell oxidative stress and myocardial tissue inflammation, which have a key role in the patho-physiology of diabetic cardiomyopathy.
Monia Savi, Leonardo Bocchi, Pedro Mena, Margherita Dall’Asta, Alan Crozier, Furio Brighenti, Donatella Stilli, Daniele Del Rio   +7 more
doaj   +1 more source

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Amyloid Beta in Alzheimer's Disease: Mechanisms, Biomarker Potential, and Therapeutic Targets

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The limited clinical efficacy of anti‐Aβ antibodies has challenged the Aβ hypothesis, compelling the integration of key mechanisms—including neuroinflammation, mitochondrial dysfunction, oxidative stress, and post‐translational modifications of Aβ—into a revised model of Alzheimer's disease.
Shamseddin Ahmadi, Shiler Khaledi, Kimia Ahmadi, Kambiz Hassanzadeh   +3 more
wiley   +1 more source

Modulatory Effects of Bifidobacterium longum Subsp. Longum BL21 on Intestinal Barrier Impairment and Metabolic Dysregulation in a Low‐Dose Dextran Sulfate Sodium‐Induced Chronic Inflammation Model

Food Bioengineering, Volume 4, Issue 4, Page 447-461, December 2025.
Abstract Chronic low‐grade intestinal inflammation is closely linked to gut barrier dysfunction and metabolic disturbance. This study established a low‐dose dextran sulfate sodium (DSS)‐induced chronic inflammation model and evaluated the protective effects of Bifidobacterium longum subsp.
Yue Huang, Yukun Sun, Yao Dong, Zhonghui Gai, Xia Gong, Qing Xia, Mei Han   +6 more
wiley   +1 more source

Pomegranate (Punica granatum L.): A medicinal plant with myriad biological properties - A short review [PDF]

, 2010
The pomegranate, Punica granatum L., which can be found throughout the Mediterranean region, in Southeast Asia, California and Arizona in USA was in ancient times referred as possessing powers of fertility, abundance and good luck (fruit). The biological
Antunes, Maria Dulce, Miguel, Maria Graça, Neves, M. A.   +2 more
core  

Randomised controlled pilot study to assess the feasibility of a Mediterranean Portfolio dietary intervention for cardiovascular risk reduction in HIV dyslipidaemia:A study protocol [PDF]

, 2016
Introduction: HIV drug treatment has greatly improved life expectancy, but increased risk of cardiovascular disease remains, potentially due to the additional burdens of infection, inflammation and antiretroviral treatment.
Frost, Gary, Garcia-Perez, Isabel, Hemming, Karla, Redwood, Sabi, Stradling, Clare, Taheri, Shahrad, Thomas, G. Neil   +6 more
core   +4 more sources

Alcohol‐Related Liver Disease and Metabolic Dysfunction‐Associated Steatotic Liver Disease: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 6, Issue 12, December 2025.
Alcohol‐related (ALD) and metabolic dysfunction‐associated (MASLD) steatotic liver disease, while initiated by distinct etiologies (ethanol vs. metabolic stress), converge on shared core pathogenic pathways that drive progression. These include dysregulated lipid metabolism, programmed cell death, cellular senescence, gut dysbiosis, and immune ...
Yupin Tan, Yirui Hu, Ye Yang, Huikuan Chu   +3 more
wiley   +1 more source