Results 21 to 30 of about 4,757 (208)
Urolithin A Protects Chondrocytes From Mechanical Overloading-Induced Injuries [PDF]
Frontiers in Pharmacology, 2021 Physiological mechanical stimulation has been shown to promote chondrogenesis, but excessive mechanical loading results in cartilage degradation. Currently, the underlying mechanotransduction pathways in the context of physiological and injurious loading are not fully understood.
Yuchen He +7 more
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Sarcopenia and Muscle Aging: A Brief Overview [PDF]
Endocrinology and Metabolism, 2020 The world is facing the new challenges of an aging population, and understanding the process of aging has therefore become one of the most important global concerns.
Tam Dao +8 more
doaj +1 more source
Ellagic Acid-Derived Urolithins as Modulators of Oxidative Stress [PDF]
Oxidative Medicine and Cellular Longevity, 2020 Oxidative stress is a state of excess of prooxidative species relative to the antioxidant defenses (enzymatic and nonenzymatic) in a living organism. The consequence of this imbalance is damage of the major cellular macromolecules (carbohydrates, lipids, proteins, and DNA), which further leads to a gradual loss of tissue and organ function. It has been
Jasmina Djedjibegovic +3 more
openaire +2 more sources
Brain Sciences, 2021 Pomegranate juice (PJ) is a rich source of ellagitannins (ETs), precursors of colonic metabolite urolithin A, which are believed to contribute to pomegranate’s neuroprotective effect.
Małgorzata Kujawska +8 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp +5 more
doaj +1 more source
Life, 2022 In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich +5 more
doaj +1 more source
Urolithin B: Two-way attack on IAPP proteotoxicity with implications for diabetes
Frontiers in Endocrinology, 2022 IntroductionDiabetes is one of the major metabolic diseases worldwide. Despite being a complex systemic pathology, the aggregation and deposition of Islet Amyloid Polypeptide (IAPP), or amylin, is a recognized histopathological marker of the disease ...
Ana F. Raimundo +15 more
doaj +1 more source
Frontiers in Microbiology, 2017 Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma +7 more
doaj +1 more source
Effects of olive and pomegranate by-products on human microbiota : a study using the SHIME (R) in vitro simulator [PDF]
, 2019 Two by-products containing phenols and polysaccharides, a "pate" (OP) from the extra virgin olive oil milling process and a decoction of pomegranate mesocarp (PM), were investigated for their effects on human microbiota using the SHIME (R) system.
Daghio, Matteo +6 more
core +1 more source
Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue
Molecules, 2022 Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo +8 more
doaj +1 more source