Results 71 to 80 of about 4,757 (208)

Persistence of anticancer activity in berry extracts after simulated gastrointestinal digestion and colonic fermentation [PDF]

, 2012
Fruit and vegetable consumption is associated at the population level with a protective effect against colorectal cancer. Phenolic compounds, especially abundant in berries, are of interest due to their putative anticancer activity.
A Gil-Izquierdo, A Gonzalez-Sarrias, A Perez-Vicente, A Petermann, Alan Crozier, AM Aura, B Holst, BN Singh, C Manach, C Parr, C Zhao, Chris I. R. Gill, Derek Stewart, DY Shin, EM Brown, EM Coates, Emma M. Brown, FJ Reyes-Zurita, FJB van Duijnhoven, G Borges, G Lala, G Williamson, Gema Pereira-Caro, GJ McDougall, GJ McDougall, Gordon J. McDougall, Ian Rowland, IT Johnson, J Ferlay, J van Duynhoven, JR Pearson, JW Yun, LA Boyd, LS Adams, M Jenner A, M Sharma, Masaru Katoh, MJ Bermudez-Soto, MJ McCann, NP Seeram, P Ramnani, Pamela Magee, PDS Spada, Philip Allsopp, PN Chen, PS Makena, R González-Barrio, Rocio González-Barrio, S Ramos, S Roowi, S Thomasset, SJ Duthie, SR Sahasrabudhe, YZ Hashim   +53 more
core   +3 more sources

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent

Antioxidants, 2020
Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries.
Guillermo Cásedas, Francisco Les, Carmen Choya-Foces, Martín Hugo, Víctor López   +4 more
doaj   +1 more source

The role of antifungals agents on Candida glabrata biofilms matrix composition [PDF]

, 2010
Candida glabrata was considered, for years, a relatively non-pathogenic saprophyte of the normal flora of healthy individuals and as no causative agent of serious infection in humans.
Azeredo, Joana, Henriques, Mariana, Lourenço, T., Negri, M., Oliveira, Rosário, Silva, Sónia Carina   +5 more
core  

Systematic analysis of the polyphenol metabolome using the Phenol-Explorer database [PDF]

, 2017
SCOPE: The Phenol-Explorer web database details 383 polyphenol metabolites identified in human and animal biofluids from 221 publications. Here we exploit these data to characterize and visualize the polyphenol metabolome, the set of all metabolites ...
Andrés Lacueva, Ma. Cristina, Barupal, Dinesh Kumar, Boto Ordóñez, María, Farran, Andreu, Llorach, Rafael, Manach, Claudine, Neveu, Vanessa, Rothwell, Joseph A., Scalbert, Augustin, Urpí Sardà, Mireia   +9 more
core   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Gut microbiota functions: metabolism of nutrients and other food components [PDF]

, 2017
The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As
A Alonso, A Belenguer, A Bordbar, A Braune, A Braune, A Duda-Chodak, A El Kaoutari, A Heinken, A Heinken, A Heinken, A Heinken, A Heinken, A Karau, A Marcobal, A Matthies, A Matthies, A Mohammed, A Quartieri, A-HM Emwas, A-M Davila, AF Hofmann, AJ Brown, AK Mallett, Almut Heinken, AR Rechner, AR Zomorrodi, AW Walker, AW Walker, B Goodwin, BE Gustafsson, BE Gustafsson, BV Jones, C Manach, C Noecker, CA Kolmeder, CA Kolmeder, CB Cole, CIR Gill, CJ Ziemer, CS Song, D Couteau, DH Mallonee, E Bauer, EA Franzosa, EA Smith, EM Lenz, EP Halmos, F Abram, F Bastos, F Suarez, F Tomas-Barberan, F Vadder De, FA Tomas-Barberan, FA Tomas-Barberan, FE Rowan, FM McIntosh, G Corona, G Falony, G Frost, G Wu, Glenn Gibson, GR Gibson, GR Gibson, GT Macfarlane, GT Macfarlane, GW Tannock, H Bernstein, H Hirokane, H Kettle, H Kettle, H Roume, H Tazoe, HM Said, I Rowland, Ian Rowland, IEJA Francois, Ines Thiele, J Eldere Van, J Pérez-Jiménez, J Trygg, JA Flick, JC Garcia-Canaveras, JC Young, JG Le Blanc, JH Cummings, JJ Eloranta, JK Nicholson, JM Landete, JM Ridlon, JM Ridlon, Jonathan Swann, JR Marchesi, JR Swann, JT Bjerrum, JW Lampe, K Decroos, K Steliou, K Watanabe, Karen Scott, Kieran Tuohy, KP Scott, KR Stayrook, L Hanske, L Hanske, L Marín, L Tasse, L Tomasova, LA Woollett, LV Hooper, M Begley, M Blaut, M Dabek, M Hermanussen, M Rajilić-Stojanović, M Vital, M Watanabe, M Watanabe, MB Biggs, MD Levitt, MGM Kok, MJ Gosalbes, MJ Hill, MV Selma, N Reichardt, NC Verberkmoes, NE Lewis, O Manor, P Kurdi, P Louis, P Louis, P Louis, P Louis, Palsson BØ, PC Pircher, PG Frick, PG Wolf, PJ Turnbaugh, Q Zhang, R Madsen, R Muñoz-Tamayo, RL Kandell, S El Aidy, S Greenblum, S Katsuma, S Lockyer, S Magnúsdóttir, S Possemiers, SA Gibson, SA Joyce, SD Boyd, SF Lajoie, SH Duncan, SH Duncan, SH Hussaini, SM Houten, SN Steinway, SU Christl, SU Christl, T Clavel, T Clavel, T Shashkova, W Xiong, W-L Wang, WR Russell, WR Russell, WR Wikoff, X Shen, X Wei, Y Wang, Z Wang, Z-L Dai, Z-L Dai   +171 more
core   +3 more sources

Separation of Isomeric Forms of Urolithin Glucuronides Using Supercritical Fluid Chromatography [PDF]

, 2023
Producción CientíficaUrolithins are gut microbiota metabolites produced in humans after consuming foods containing ellagitannins and ellagic acid. Three urolithin metabotypes have been reported for different individuals depending on the final urolithins ...
Althobaiti, Yusuf, Ares Sacristán, Ana María, Bernal del Nozal, José, García Villalba, Rocío, Tomás Barberán, Francisco A., Toribio Recio, Laura, Villalgordo, Jose M.   +6 more
core   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Development of personalised functional foods needs metabolic profiling [PDF]

, 2014
Purpose of review There is growing interest in applying metabolic profiling technologies to food science as this approach is now embedded into the foodomics toolbox. This review aims at exploring how metabolic profiling can be applied to the development
Claus, Sandrine Paule
core   +1 more source