Results 61 to 70 of about 22,193 (229)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Membrane proteins in the outer mebrane of plastids and mitochondria [PDF]

open access: yes, 2006
Channels of the plastid and mitochondrial outer membranes facilitate the turnover of molecules and ions via these membranes. Although channels have been studied many questions pertaining to the whole diversity of plastid and mitochondrial channels in ...
Ilkavets, Iryna
core  

Gain Stabilization of a Submillimeter SIS Heterodyne Receiver

open access: yes, 2007
We have designed a system to stabilize the gain of a submillimeter heterodyne receiver against thermal fluctuations of the mixing element. In the most sensitive heterodyne receivers, the mixer is usually cooled to 4 K using a closed-cycle cryocooler ...
Battat, James   +5 more
core   +1 more source

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. [PDF]

open access: yes, 2019
Gasdermin E (GSDME/DFNA5) cleavage by caspase-3 liberates the GSDME-N domain, which mediates pyroptosis by forming pores in the plasma membrane.
Alnemri, Emad S.   +5 more
core   +3 more sources

The use of anti-VDAC2 antibody for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced acrosome reaction.

open access: yesPLoS ONE, 2011
Voltage-dependent anion channel (VDAC) is mainly located in the mitochondrial outer membrane and participates in many biological processes. In mammals, three VDAC subtypes (VDAC1, 2 and 3) have been identified.
Bianjiang Liu   +3 more
doaj   +1 more source

Reward history modulates perceptual load effects

open access: yesActa Psychologica, 2021
The reward history of a stimulus can yield strong attentional selection biases. Indeed, attentional capture can be triggered by previously rewarded items which are neither salient nor relevant for the ongoing task, even when selection is clearly counter ...
Jérémy Matias   +4 more
doaj   +1 more source

Aging cellular networks: chaperones as major participants

open access: yes, 2006
We increasingly rely on the network approach to understand the complexity of cellular functions. Chaperones (heat shock proteins) are key "networkers", which have among their functions to sequester and repair damaged protein. In order to link the network
Agoston   +56 more
core   +1 more source

Voltage Dependent Anion Channel Is Redistributed during Japanese Encephalitis Virus Infection of Insect Cells

open access: yesThe Scientific World Journal, 2014
Despite the availability of an effective vaccine, Japanese encephalitis remains a significant cause of morbidity and mortality in many parts of Asia.
Chanida Fongsaran   +5 more
doaj   +1 more source

Proteomic Shifts Reflecting Oxidative Stress and Reduced Capacity for Protein Synthesis, and Alterations to Mitochondrial Membranes in Neurospora crassa Lacking VDAC

open access: yesMicroorganisms, 2022
Voltage-dependent anion-selective channels (VDAC) maintain the bidirectional flow of small metabolites across the mitochondrial outer membrane and participate in the regulation of multiple cellular processes.
Sabbir R. Shuvo   +4 more
doaj   +1 more source

Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR [PDF]

open access: yes, 2014
The human voltage dependent anion channel 1 (VDAC) is a 32 kDa β-barrel integral membrane protein that controls the transport of ions across the outer mitochondrial membrane.
Andreas, Loren   +8 more
core   +1 more source

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