Single fibre cytoarchitecture in ventilator-induced diaphragm dysfunction (VIDD) assessed by quantitative morphometry second harmonic generation imaging: Positive effects of BGP-15 chaperone co-inducer and VBP-15 dissociative corticosteroid treatment [PDF]
Frontiers in Physiology, 2023 Ventilator-induced diaphragm dysfunction (VIDD) is a common sequela of intensive care unit (ICU) treatment requiring mechanical ventilation (MV) and neuromuscular blockade (NMBA).
Dominik Schneidereit +2 more
exaly +7 more sources
Unveiling the Functions of the VosA-VelB Target GenevidDinAspergillus nidulans [PDF]
Mycobiology, 2021 The velvet regulators VosA and VelB are primarily involved in spore maturation and dormancy. Previous studies found that the VosA-VelB hetero-complex coordinates certain target genes that are related to fungal differentiation and conidial maturation in ...
Hee-Soo Park
exaly +4 more sources
The Egyptian Journal of Chest Diseases and Tuberculosis, 2017 Background: There is increasing awareness that diaphragm weakness is common in patients undergoing MV and is likely a contributing cause of weaning failure.
Eman Ramzy Ali, Ahmad Mostafa Mohamad
exaly +4 more sources
Research progress on the pathogenesis and treatment of ventilator-induced diaphragm dysfunction [PDF]
Heliyon, 2023 Prolonged controlled mechanical ventilation (CMV) can cause diaphragm fiber atrophy and inspiratory muscle weakness, resulting in diaphragmatic contractile dysfunction, called ventilator-induced diaphragm dysfunction (VIDD).
Jumei Zhang +5 more
doaj +2 more sources
Association of diaphragmatic dysfunction with duration of mechanical ventilation in patients in the pediatric intensive care unit: a prospective cohort study [PDF]
BMC PediatricsBackground Mechanical ventilation (MV) can cause diaphragmatic injury and ventilator induced diaphragmatic dysfunction (VIDD). Diaphragm ultrasonography (DU) is increasingly used to assess diaphragmatic anatomy, function and pathology of patients ...
Yelin Yao +8 more
doaj +2 more sources
Identification of competing endogenous RNA networks involved in phrenic nerve stimulation preventing mechanical ventilation induced diaphragm dysfunction [PDF]
Scientific ReportsVentilator-induced diaphragmatic dysfunction (VIDD) is characterized by diaphragmatic atrophy and contractile failure, leading to prolonged intensive care unit (ICU) stays and increases mortality.
Mingming Zhang +6 more
doaj +2 more sources
Treatment with levosimendan in an experimental model of early ventilator-induced diaphragmatic dysfunction [PDF]
Drug Target Insights, 2023 Introduction: Mechanical ventilation (MV) is a life-saving approach in critically ill patients. However, it may affect the diaphragmatic structure and function, beyond the lungs.
Vanessa Zambelli +6 more
doaj +2 more sources
Journal of Cachexia, Sarcopenia and Muscle, 2019 Background Mechanical ventilation (MV) is a life‐saving measure for patients in respiratory failure. However, prolonged MV results in significant diaphragm atrophy and contractile dysfunction, a condition referred to as ventilator‐induced diaphragm ...
Bumsoo Ahn +2 more
exaly +2 more sources
Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways [PDF]
BMC Pulmonary Medicine, 2023 Background Mechanical ventilation can cause acute atrophy and injury in the diaphragm, which are related to adverse clinical results. However, the underlying mechanisms of ventilation-induced diaphragm dysfunction (VIDD) have not been well elucidated ...
Weimin Shen +10 more
doaj +2 more sources
Identification of key genes affecting ventilator-induced diaphragmatic dysfunction in diabetic mice [PDF]
Frontiers in GeneticsBackgroundMechanical ventilation (MV) is often required in critically ill patients. However, prolonged mechanical ventilation can lead to Ventilator-induced diaphragmatic dysfunction (VIDD), resulting in difficulty in extubation after tracheal intubation,
Rongchun Xing +11 more
doaj +2 more sources