Results 121 to 130 of about 485 (131)
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International Journal of Biological Macromolecules
Since recombinant biotherapeutics were accepted in the therapeutic drug market, one of the significant challenges has been the insufficient circulatory half-life of many protein and peptide-based drugs. To overcome this pharmacokinetic limitation, serum albumin has been widely utilized as a molecular carrier due to its intrinsic FcRn-mediated recycling
Peiyu, Hao +7 more
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Since recombinant biotherapeutics were accepted in the therapeutic drug market, one of the significant challenges has been the insufficient circulatory half-life of many protein and peptide-based drugs. To overcome this pharmacokinetic limitation, serum albumin has been widely utilized as a molecular carrier due to its intrinsic FcRn-mediated recycling
Peiyu, Hao +7 more
openaire +2 more sources
Development of idiotype-specific vNAR-CAR-immune cells for the treatment of clonal malignancies
Klinische Pädiatrie, 2022P Wendel +8 more
openaire +1 more source
In vitro selection of VNAR antibodies using bioinformatics-based library design and cDNA display
Variable domains of new antigen receptors (VNARs) derived from shark immunoglobulin new antigen receptors (IgNARs) have gained attention as promising single-domain antibody modalities owing to their compact structure, structural stability, and unique binding capabilities. This study aimed to present a novel approach for VNAR discovery using a syntheticHiroki Anzai +10 more
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Cytoplasmic and periplasmic expression of recombinant shark VNAR antibody in Escherichia coli
Preparative Biochemistry and Biotechnology, 2019Katja Fischer +2 more
exaly