Results 91 to 100 of about 8,482 (180)

Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis

, 2006
Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells. Therefore, a tight regulation of this process is essential. Cell shrinkage
openaire   +1 more source

Functional Differences among Wheat Voltage-dependent Anion Channel (VDAC) Isoforms Expressed in Yeast [PDF]

Journal of Biological Chemistry, 1997
Adi Elkeles, Adina Breiman, Martin Zizi
openaire   +1 more source

Mitochondrial voltage-dependent anion-selective channel (VDAC): a global player in cells.

, 2016
Mitochondria are primary ATP producing organelles and are involved in many cellular signalling pathways. Mitochondrial porin, which forms voltage-dependent anion-selective channels (VDAC) in the mitochondrial outer membrane (MOM), can be folded into a 19 β-stranded barrel.
openaire   +1 more source

Three mammalian VDAC isoforms distinctly regulate mitochondrial function and proteome to maintain cell metabolism. [PDF]

J Biol Chem
Rajendran M, Rosencrans WM, Bautista NA, Fitzgerald W, Huynh D, Beyene BG, Quan B, Petersen JD, Hwang J, Chou TF, Bezrukov SM, Rostovtseva TK.   +11 more
europepmc   +1 more source

Cannabidiol Regulates CD47 Expression and Apoptosis in Jurkat Leukemic Cells Dependent upon VDAC-1 Oligomerization. [PDF]

Pharmaceuticals (Basel)
Wang L, Samarani S, Fadzeyeva E, Vigano M, As'sadiq A, Vulesevic B, Ahmad A, Costiniuk CT.   +7 more
europepmc   +1 more source

TrkB Overexpression via Gene Therapy: Enhanced Optic Nerve Uptake With Associated Increases in Mitochondria and Axoplasmic Transport. [PDF]

Cureus
Yazdouni S, Osborne A, Martin KR.
europepmc   +1 more source

Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review). [PDF]

Mol Med Rep
Wang J, Liang Y, Jia X, Yang X, Shi D, Wang Y, Pan Y.   +6 more
europepmc   +1 more source

Proteomic screening of TMEM43 binding partners identifies VDAC leading to mitochondrial dysfunction. [PDF]

PLoS One
Zhu Q, Zheng G, Lu Y, Jiang Y, Li Y, Chen H, Huang L, Tang N, Li B, Lu Y, Zhang J, Zhu C.   +11 more
europepmc   +1 more source

The voltage-dependent anion channel (VDAC) binds tissue-type plasminogen activator and promotes activation of plasminogen on the cell surface. [PDF]

J Biol Chem, 2013
Gonzalez-Gronow M, Ray R, Wang F, Pizzo SV.   +3 more
europepmc   +1 more source

A small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis. [PDF]

Nat Commun
Yan W, Talley DC, Syam A, Danchik C, Zhong Y, Zhang X, Liu X, Baljinnyam B, Kales SC, Cyr MG, Fang Y, Zakharov AV, Hu X, Niehoff T, Xu T, Qu Y, Yang A, Courouble VV, Yao Q, Simeonov A, Huang R, Rostovtseva TK, Bezrukov SM, LeClair CA, Egan JM, Wang H, Tao D, Rai G, Henderson MJ, Fang S.   +29 more
europepmc   +1 more source