Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. [PDF]
The ability of azobenzene trimethylammonium bromide (azoTAB) to sensitize cardiac tissue excitability to light was recently reported. The dark, thermally relaxed trans- isomer of azoTAB suppressed spontaneous activity and excitation propagation speed ...
Sheyda R Frolova +4 more
doaj +1 more source
Sea anemones produce venoms characterized by a complex mixture of low molecular weight compounds, proteins and peptides acting on voltage-gated ion channels. Mammal sperm cells, like neurons, are characterized by their ion channels. Calcium channels seem
Fernando Lazcano-Pérez +12 more
doaj +1 more source
Ion channel gating: a first passage time analysis of the Kramers type [PDF]
The opening rate of voltage-gated potassium ion channels exhibits a characteristic, knee-like turnover where the common exponential voltage-dependence changes suddenly into a linear one.
Blatz +12 more
core +4 more sources
Cnidarian Toxins Acting on Voltage-Gated Ion Channels
: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review
Robert M. Greenberg, Shanta M. Messerli
doaj +1 more source
An evolutionarily-unique heterodimeric voltage-gated cation channel found in aphids [PDF]
We describe the identification in aphids of a unique heterodimeric voltage-gated sodium channel which has an atypical ion selectivity filter and, unusually for insect channels, is highly insensitive to tetrodotoxin.
Amey, Joanna S. +9 more
core +1 more source
Emerging Roles of L-Type Voltage-Gated and Other Calcium Channels in T Lymphocytes [PDF]
In T lymphocytes, calcium ion controls a variety of biological processes including development, survival, proliferation, and effector functions. These distinct and specific roles are regulated by different calcium signals, which are generated by various ...
Abdallah eBadou +4 more
core +2 more sources
Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains [PDF]
Voltage-gated channels open paths for ion permeation upon changes in membrane potential, but how voltage changes are coupled to gating is not entirely understood.
Barros de la Roza, Francisco +8 more
core +1 more source
Voltage-Gated Potassium Channels as Regulators of Cell Death
Ion channels allow the flux of specific ions across biological membranes, thereby determining ion homeostasis within the cells. Voltage-gated potassium-selective ion channels crucially contribute to the setting of the plasma membrane potential, to volume
Magdalena Bachmann +9 more
doaj +1 more source
Voltage-dependent gating in a "voltage sensor-less" ion channel. [PDF]
The voltage sensitivity of voltage-gated cation channels is primarily attributed to conformational changes of a four transmembrane segment voltage-sensing domain, conserved across many levels of biological complexity.
Harley T Kurata +4 more
doaj +1 more source
Comparison of Langevin and Markov channel noise models for neuronal signal generation
The stochastic opening and closing of voltage-gated ion channels produces noise in neurons. The effect of this noise on the neuronal performance has been modelled using either approximate or Langevin model, based on stochastic differential equations or ...
A. L. Hodgkin +15 more
core +1 more source

