Results 11 to 20 of about 1,755 (175)
Ashwagandha Root Extract and Its Potential Modulation of CCN1‐Associated Pathways in Sensitive‐Skin Aging [PDF]
J Cosmet DermatolABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Kang L +13 more
europepmc +2 more sources
Heliyon, 2023 Introduction: Withania somnifera (WS) or ashwagandha is an adaptogenic plant used extensively in traditional medicines and as a food supplement. Despite a long history of use and numerous clinical trials, the human pharmacokinetics of withanolides, the ...
Se-Kwon Kim +3 more
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Molecules, 2022 Withania somnifera is a traditional Indian herb described under the ‘Rasayana’ class in Ayurveda, which gained immense popularity as a dietary supplement in the USA, Europe, Asia, and the Indian domestic market.
Siddharth J. Modi +9 more
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QUANTITIVE EVOLUTION OF WITHANOLIDES CONTENT OF EGYPTIAN WITHANIA SOMNIFERA (L.) ROOTS. [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2013 Withanolides are important secondary metabolite in Withania somnifera (L.), which have high medicinal values and possess potent anti-tumor and antioxidant properties.
Said Ismail
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Molecules, 2022 Natural products are a major source of biologically active compounds that make promising lead molecules for developing efficacious drug-like molecules.
Amandeep Singh +4 more
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Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor. [PDF]
PLoS ONE, 2014 The present study investigated the biosynthesis of major and minor withanolides of Withania somnifera in cell suspension culture using shake-flask culture and bioreactor by exploiting elicitation and precursor feeding strategies.
Ganeshan Sivanandhan +3 more
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Electronic Journal of Plant Breeding, 2023 Fourty-eight ashwagandha [Withania somnifera (L.) Dunal] genotypes were studied for the genetic variability, heritability and trait association during 2018-19 based on 13 yield and quality traits. For all the 13 characters studied, highly significant
Venna Santhosh1,3*, B. Prem Kumar2 , B. Pratibha3 , L. Sampath4 and Akarsh Parihar3
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Withania somnifera L.: Insights into the phytochemical profile, therapeutic potential, clinical trials, and future prospective [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Withania somnifera L. is a multipurpose medicinal plant of family Solanaceae occurring abundantly in sub-tropical regions of the world. The folk healers used the plant to treat several diseases such as fever, cancer, asthma, diabetes, ulcer, hepatitis ...
Sumaira Saleem +4 more
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Withanolides and Related Steroids [PDF]
, 2011 Since the isolation of the first withanolides in the mid-1960s, over 600 new members of this group of compounds have been described, with most from genera of the plant family Solanaceae. The basic structure of withaferin A, a C28 ergostane with a modified side chain forming a δ-lactone between carbons 22 and 26, was considered for many years the basic ...
Misico, Rosana Isabel +5 more
openaire +3 more sources
PLoS ONE, 2012 Withanolides are a large group of steroidal lactones found in Solanaceae plants that exhibit potential anticancer activities. We have previously demonstrated that a withanolide, tubocapsenolide A, induced cycle arrest and apoptosis in human breast cancer
Hui-Chun Wang +6 more
doaj +1 more source