Results 31 to 40 of about 2,611 (169)
Antiproliferative Withanolides from Datura wrightii [PDF]
, 2012 A new withanolide, named withawrightolide (1), and four known withanolides (2−5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques.
Joseph Bazzill +17 more
core +1 more source
Withanolides and related steroids [PDF]
, 2011 Since the isolation of the first withanolides in the mid-1960s, over 600 new members of this group of compounds have been described, with most from genera of the plant family Solanaceae.
Barboza, Gloria Estela +12 more
core +1 more source
New Spiranoid Withanolides From Jaborosa Odonelliana [PDF]
, 2000 From whole Jaborosa odonelliana plants four new withanolides containing a spiranic lactone in the side chain, were isolated and their structures elucidated by spectroscopic ...
G. Burton +7 more
core +2 more sources
Journal of Advanced Pharmaceutical Technology & Research, 2015 Withania somnifera (L.) Dunal, shows several pharmacological properties which are attributed mainly to the withanolides present in the root. The efficacy of medicinally active withanolides constituents depends on the absorption and transportation through
Santosh T Devkar +8 more
doaj +1 more source
Antiproliferative withanolides from several Solanaceous species [PDF]
, 2014 This is an Accepted Manuscript of an article published by Taylor & Francis in Natural Product Research in November 2014, available online: http://www.tandfonline.com/10.1080/14786419.2014.919286.To date, our work on Solanaceous species (Datura wrightii ...
Timmermann, Barbara N. +3 more
core +1 more source
Phytotoxic withanolides from Jaborosa rotacea [PDF]
, 2006 Twelve new withanolides were isolated from the aerial part of Jaborosa rotacea: five had a spiranoid delta-lactone ( 1- 5); one contained a 26,12-delta-lactone and a C-12-C-23 bond ( 6); five corresponded to trechonolide-type withanolides with ...
Feresin, Gabriela Egly +13 more
core +3 more sources
Frontiers in Bioscience-Landmark, 2022 Background: Many drugs for anti-tumour have been developed, nevertheless, seeking new anticancer drug is the focus of ongoing investigation. Withanolides have been reported to possess potent antiproliferative activity. Literature findings revealed that a
Qian-Ran Li +10 more
doaj +1 more source
Isolation and characterisation of irinans, androstane-type withanolides from L. [PDF]
, 2019 Withanolides are steroidal lactones widespread in Nightshade plants with often potent antiproliferative activities. Additionally, the structural diversity of this compound class holds much potential for the discovery of novel biological activity.
Franke, Jakob +4 more
core +1 more source
Molecules, 2021 Chagas disease (CD) affects more than 6 million people worldwide. The available treatment is far from ideal, creating a demand for new alternative therapies. Botanical diversity provides a wide range of novel potential therapeutic scaffolds.
Raiza B. Peres +8 more
doaj +1 more source
De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. [PDF]
PLoS ONE, 2013 Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides.
Parul Gupta +7 more
doaj +1 more source