Results 111 to 120 of about 89,320 (324)

Uji Penghambatan Xantin Oksidase Secara In Vitro Ekstrak Kulit Rambutan

Pharmaceutical Sciences and Research, 2016
Hyperuricemia is a condition that uric acid levels increased and cause accumulated uric acid crystals in the tissues. Xanthine oxidase is an enzyme which catalyze the oxidation of hypoxanthine into xanthine and into uric acid.
Nurul Eka Putri, Rissyelly, Marista Gilang Mauldina   +2 more
doaj   +1 more source

Collaborative Expert LLMs Guided Multi-Objective Molecular Optimization [PDF]

arXiv
Molecular optimization is a crucial yet complex and time-intensive process that often acts as a bottleneck for drug development. Traditional methods rely heavily on trial and error, making multi-objective optimization both time-consuming and resource-intensive. Current AI-based methods have shown limited success in handling multi-objective optimization
arxiv  

XANTHINE OXIDASE ACTIVITY IN REGENERATING LIVER [PDF]

, 1957
Muriel Feigelson, Philip Feigelson, Paul R. Gross   +2 more
openalex   +1 more source

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

iMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu, Hyein Jung, Fouad Choueiry, Shiqi Zhang, Rachel Pearlman, Heather Hampel, Ning Jin, Jieli Li, Jiangjiang Zhu   +8 more
wiley   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

iMetaOmics, EarlyView.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang, Zeng Zhang, Mohan Chen, Jin Hu, Yingqi Qiu, Shijia Lin, Xiaolu Zhou, Jiachao Zhang, Shuaiming Jiang   +8 more
wiley   +1 more source

Ueber das Xanthin [PDF]

Justus Liebigs Annalen der Chemie
n ...
openaire   +6 more sources

Ruthenium Nanozyme@Magnesium silicate nanosheets encapsuled in microneedle patches promote repair of radiation‐induced skin defects by remodeling pathological environment

Interdisciplinary Medicine, EarlyView.
In this work, we introduce a novel composite microneedle (MN) patch that integrates ruthenium‐loaded magnesium silicate nanosheets (MSR) as a multifaceted therapeutic platform with oxidative stress mitigation, ROS generation inhibition and cellular signaling pathways restoration for treating RISD.
Zhongyi Sun, Haibo Liu, Mengting Yin, Ningning Cheng, Wencheng Liu, Kangkang Zhao, Hua Zeng, Xuming Chen, Zijie Wang, Xuhui Zhou, Xinyu Zhao, Feng Chen   +11 more
wiley   +1 more source

Characterization of xanthine oxidase inhibitory activities of phenols from pickled radish with molecular simulation

Food Chemistry: X, 2022
Pickled radish is a general source of natural bioactive compounds that include phenols. Here, we used molecular docking, fluorescence quenching, circular dichroism spectroscopy and molecular dynamics simulations to identify potential inhibitors against ...
Xiaoze Liu, Daren Wu, Jingwen Liu, Guiling Li, Zhengxiao Zhang, Chaoxiang Chen, Lingyu Zhang, Jian Li   +7 more
doaj  

Functional Polymers and Their Nanocomposites for Sustainable Packaging Applications

Macromolecular Materials and Engineering, EarlyView.
This study provides recent advances and knowledge gaps related to developing plastics‐based sustainable packaging materials across various segments, focusing on the intervention of functionality and nanotechnology and their impact on sustainability. Abstract This study explores recent advances and knowledge gaps in developing sustainable plastics‐based
Ritima Banerjee, Jayita Bandyopadhyay, Suprakas Sinha Ray   +2 more
wiley   +1 more source

The reduction of cytochrome c by hypoxanthine and xanthine oxidase [PDF]

, 1952
D.B. Morell
openalex   +1 more source