Results 121 to 130 of about 107,799 (290)
AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li +5 more
wiley +1 more source
Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun +2 more
wiley +1 more source
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn +12 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
Infusion pasteurization of skim milk: Effects of different time-temperature combinations [PDF]
Infusion pasteurization technology was used in different time-temperature combinations for heat treatment of skim milk and compared to untreated skim milk and a standard pasteurization treatment.
Hammershøj, M. +2 more
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Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi +4 more
wiley +1 more source
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
wiley +1 more source
Optimal timing to assess exercise‐induced oxidative stress: A systematic review and meta‐analysis
Abstract There is a lack of consensus on optimal timing to assess redox biomarkers post‐exercise, limiting methodological standardisation and linking oxidative stress to physiology. We determined optimal post‐exercise oxidative stress assessment times using three redox biomarkers: glutathione, F2‐isoprostanes and protein carbonyls.
Chrysovalantis Stachteas +12 more
wiley +1 more source
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a major public health concern, largely driven by the high‐fat, high‐sugar and low‐fibre Western diet. The Western diet is often accompanied by binge drinking, or the rapid consumption of alcohol in a short time leading to a blood alcohol concentration of ≥0.08%.
Ihsan Shawki Akili +14 more
wiley +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source

