Neutrophil Gelatinase-associated Lipocalin, Cystatin C and Matrix Metalloproteinase-9 as Possible Biomarkers in Early Detection of Acute Kidney Injury after Cardiac Surgery [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Acute Kidney Injury (AKI) often occurs after open heart surgery. Today, serum creatinine is used as an indicator for identifying AKI; however, creatinine is unreliable due to delay in its elevation.
Sara Bagheri +5 more
doaj +1 more source
Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury. [PDF]
, 2013 The small intestine plays a key role in the pathogenesis of multiple organ failure following circulatory shock. Current results show that reduced perfusion of the small intestine compromises the mucosal epithelial barrier, and the intestinal contents ...
Altshuler, Angelina E +5 more
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MMP2 Sheds Glypican‐4 to Suppress Slit3‐Robo4 Signaling and Angiogenesis
Proteoglycan Research, Volume 4, Issue 1, January 2026.ABSTRACT Axon guidance molecules, initially identified for their roles in neural development, are now recognized as crucial regulators of angiogenesis and blood vessel patterning. Among these, Slit3 promotes endothelial cell migration, proliferation, and vascular network formation by signaling through the endothelial‐specific receptor Robo4.
Wenyuan Xiao +5 more
wiley +1 more source
AnimalsHigh-fat diets are commonly used in fish farming due to their protein-sparing effect, contributing to reduced production costs. However, this practice may have adverse effects such as metabolic impairment and inflammation.
Irene García-Meilán +8 more
doaj +1 more source
Temporal and spatial expression of tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1 and -2) in the bovine corpus luteum [PDF]
, 2003 The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the corpus luteum (CL) over the course of its life span.
Moses, Marsha A. +2 more
core +3 more sources
European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.Abstract Background Interstitial lung diseases (ILDs) are characterized by progressive fibrosis, in which extracellular matrix remodelling is regulated by matrix metalloproteinases (MMPs) and their inhibitors (TIMPs). The MMP‐9/TIMP‐1 balance has been implicated in fibrogenesis, but its role in human ILD remains incompletely defined.
Maria Bertolotto +13 more
wiley +1 more source
Makara Seri Sains, 2010 Purification and Characterization of Fibrinolytic Proteases from Mushroom Volvariela volvaceae Extract. Ediblestraw mushroom (V. volvaceae) has been known used for improvement of blood circulation due to its fibrinolyticcontent.
Willy Praira +3 more
doaj
Zymographic techniques for the analysis of matrix metalloproteinases and their inhibitors
BioTechniques, 2005 The balance between matrix metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), is largely responsible for the remodeling of tissues.
Patricia A.M. Snoek-van Beurden +1 more
doaj +1 more source
M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. [PDF]
, 2017 Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated the favourable effects of liver fibrosis against acute insults.
Bai, Li +13 more
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Effects of arginine vasopressin deficiency on cardiac fibrosis in male Wistar rats
Physiological Reports, Volume 14, Issue 2, January 2026.Abstract Cardiac fibrosis represents a consequence of hypertensive heart disease and is associated with ventricular dysfunction, arrhythmias, and mortality. Arginine vasopressin (AVP) promotes myofibroblast proliferation and collagen synthesis through V1a receptors.
A. Limón‐Mendoza +7 more
wiley +1 more source