Results 141 to 150 of about 14,756 (172)

Elucidation of critical chemical moieties of metallo-β-lactamase inhibitors and prioritisation of target metallo-β-lactamases. [PDF]

J Enzyme Inhib Med Chem
Lee JH, Kim SG, Jang KM, Shin K, Jin H, Kim DW, Jeong BC, Lee SH.   +7 more
europepmc   +1 more source

In-vitro activity of newly-developed β-lactamase inhibitors avibactam, relebactam and vaborbactam in combination with anti-pseudomonal β-lactam antibiotics against AmpC-overproducing clinical Pseudomonas aeruginosa isolates. [PDF]

Eur J Clin Microbiol Infect Dis
Le Terrier C, Raro OHF, Saad AM, Nordmann P, Poirel L.   +4 more
europepmc   +1 more source

Relative inhibitory activities of newly developed diazabicyclooctanes, boronic acid derivatives, and penicillin-based sulfone β-lactamase inhibitors against broad-spectrum AmpC β-lactamases. [PDF]

Antimicrob Agents Chemother
Le Terrier C, Mlynarcik P, Sadek M, Nordmann P, Poirel L.   +4 more
europepmc   +1 more source

Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. [PDF]

J Med Chem
Villamil V, Rossi MA, Mojica MF, Hinchliffe P, Martínez V, Castillo V, Saiz C, Banchio C, Macías MA, Spencer J, Bonomo RA, Vila A, Moreno DM, Mahler G.   +13 more
europepmc   +1 more source

Antimicrobial and Diagnostic Stewardship of the Novel β-Lactam/β-Lactamase Inhibitors for Infections Due to Carbapenem-Resistant Enterobacterales Species and Pseudomonas aeruginosa. [PDF]

Antibiotics (Basel)
Ferous S, Anastassopoulou C, Pitiriga V, Vrioni G, Tsakris A.   +4 more
europepmc   +1 more source

Assessment of the activity and mechanisms of resistance to cefiderocol and combinations of β-lactams and the novel β-lactamase inhibitors avibactam, taniborbactam, zidebactam, nacubactam, xeruborbactam, and ANT3310 in emerging double-carbapenemase-producing Enterobacterales. [PDF]

Antimicrob Agents Chemother
Blanco-Martín T, López-Hernández I, Aracil B, González-Pinto L, Aja-Macaya P, Alonso-García I, Rodríguez-Pallares S, Sánchez-Peña L, Outeda-García M, Pérez-Vázquez M, Vázquez-Ucha JC, Beceiro A, Pascual Á, Bou G, López-Cerero L, Oteo-Iglesias J, Arca-Suárez J, GEMARA-SEIMC/CIBERINFEC Study Group on the activity and resistance mechanisms to new β-lactams and β-lactamase inhibitors (PROTECT).   +17 more
europepmc   +1 more source

Development and Validation of a Capillary Zone Electrophoresis-Tandem Mass Spectrometry Method for Simultaneous Quantification of Eight β-Lactam Antibiotics and Two β-Lactamase Inhibitors in Plasma Samples. [PDF]

Pharmaceuticals (Basel)
Cizmarova I, Mikus P, Svidrnoch M, Piestansky J.   +3 more
europepmc   +1 more source

Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in <i>in vitro</i> media, and novel supplement dosing strategy to mitigate thermal drug degradation. [PDF]

Antimicrob Agents Chemother
Zhou J, Qian Y, Lang Y, Zhang Y, Tao X, Moya B, Sayed ARM, Landersdorfer CB, Shin E, Werkman C, Smith NM, Kim TH, Kumaraswamy M, Shin BS, Tsuji BT, Bonomo RA, Lee RE, Bulitta JB.   +17 more
europepmc   +1 more source

Synthesis and molecular docking analysis of MBH adducts' derived amides as potential β-lactamase inhibitors. [PDF]

Bioinformation
Ullah H, Majid S, Abro A, Rahman TU, Khan AM, Ahmed M, Asif M, Yousafzai A, Ullh R, Pushparaj PN, Rasool M.   +10 more
europepmc   +1 more source