Results 1 to 10 of about 7,707 (195)

Enantiomer stability of atropisomeric 1,5-disubstituted 1,2,3-triazoles [PDF]

open access: yesTetrahedron Chem, 2022
The synthesis and characterisation of axially chiral atropisomeric 1,5-disubstituted 1,2,3-triazoles is reported. Molecules designed to display restricted rotation about 1,2,3-triazole N-1-aryl or 1,2,3-triazole C-5-aryl bonds were investigated by ...
Fernanda Meloni   +6 more
doaj   +3 more sources

Synthesis and Ring-Chain Tautomerism of 1-(4-Ethoxyphenyl)-5-formyl-1H-1,2,3-triazole-4-carboxylic Acid: The First Representative of a 5-Formyl-1H-1,2,3-triazole-4-carboxylic Acids Series

open access: yesMolbank, 2022
Synthesis of the first representative of a 5-formyl-1H-1,2,3-triazole-4-carboxylic acids series – 1-(4-ethoxyphenyl)-5-formyl-1H-1,2,3-triazole-4-carboxylic acid was performed.
Nazariy T. Pokhodylo, Mykola D. Obushak
doaj   +1 more source

1,2,3-Triazole-4(5)-amines – Convenient Synthetic Blocks for the Construction of Triazolo-Annulated Heterocycles

open access: yesЖурнал органічної та фармацевтичної хімії, 2022
Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota   +3 more
doaj   +1 more source

5-Formyltriazoles as Valuable Starting Materials for Unsymmetrically Substituted Bi-1,2,3-Triazoles

open access: yesFrontiers in Chemistry, 2020
Herein, we present the first synthetic methodologies toward non-symmetrical 5,5′-C, C-linked bi-1,2,3-triazoles starting from 5-formyl-1,2,3-triazole via two related pathways.
Robby Vroemans   +3 more
doaj   +1 more source

Combination of 1,2,3-triazole and 1,2,4-triazole frameworks for new high-energy and low-sensitivity compounds

open access: yesEnergetic Materials Frontiers, 2021
s: In this study, a series of energetic compounds based on C–C linked 1,2,3-triazole and 1,2,4-triazole were synthesized and characterized, i.e., 5-(5-nitro-2H-1,2,3-triazole-4-yl)-4H-1,2,4-triazole-3,4-diamine (compound 1), N-(3-amino-5-(5-nitro-2H-1,2 ...
Wenjing Yao   +4 more
doaj   +1 more source

1-(4-Nitrophenyl)-1H-1,2,3-Triazole-4-carbaldehyde: Scalable Synthesis and Its Use in the Preparation of 1-Alkyl-4-Formyl-1,2,3-triazoles

open access: yesOrganics, 2021
1,2,3-Triazole-4-carbaldehydes are useful synthetic intermediates which may play an important role in the discovery of novel applications of the 1,2,3-triazole moiety.
Tomas Opsomer   +3 more
doaj   +1 more source

One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction

open access: yesChemistry Proceedings, 2023
Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifungal,
Fidel Rodriguez-Lopez   +3 more
doaj   +1 more source

A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities

open access: yesJournal of Pharmaceutical Research, 2023
The largest family of organic molecules in organic chemistry are heterocyclic compounds. A heterocyclic compound is created when an oxygen, nitrogen, sulphur, or atom of a similar element is included in place of a carbon atom.
C Geethapriya Loganathan   +4 more
doaj   +1 more source

Reaction of 4-acetyl-1,2,3-triazol-5-olate with hydrazine derivatives

open access: yesChimica Techno Acta, 2015
1,2,3-triazole attracts attention because of the ability opening ring to form α-diazoimin and intramolecular rearrangements with the formation of various heterocyclic systems.
I. S. Khazhieva   +2 more
doaj   +1 more source

Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

open access: yesBeilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin   +7 more
doaj   +1 more source

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