Results 71 to 80 of about 7,707 (195)

Sensitive Energetics from the N‐Amination of 4‐Nitro‐1,2,3‐Triazole

open access: yesChemistryOpen, 2020
Energetic N‐amino‐C‐nitro compounds 1‐amino‐4‐nitro‐1,2,3‐triazole and 2‐amino‐4‐nitro‐1,2,3‐triazole are characterized for the first time as energetic materials. These compounds were characterized chemically by nuclear magnetic resonance (NMR), Infrared
Dominique R. Wozniak   +4 more
doaj   +1 more source

Transformations of 1-(Oxiranylmethyl)-1,2,3-triazoles into 2-(Oxiranyl­methyl)-1,2,3-triazoles and Alkanenitriles [PDF]

open access: yesSynlett, 2012
New reactions for the transformation of 1-(oxiranylmethyl)-1,2,3-triazoles into 2-(oxiranylmethyl)-1,2,3-triazoles or alkanenitriles were established. Successive treatment of the substrate with triflic acid and t-BuOH afforded 4,6-dihydro-5-hydroxy-1,3a,6a-triazapentalene derivative.
Osawa, Ayumi   +3 more
openaire   +3 more sources

Cu(I)‐Catalyzed Interrupted Cycloaddition Between Azides, Ag(I)‐Acetylides, and Diorganoyl Dichalcogenides

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Unleashing the power of Ag(I)‐acetylides with LiCl/dimethyl sulfoxide (DMSO). The LiCl/DMSO mixture have an unexplored ability to dramatically increase the solubility of Ag(I)‐acetylides regardless of their molecular structure, which is explored to achieve high chemoselectivity in the Cu(I)‐catalyzed interrupted cycloaddition between organic azides, Ag(
Diego Seckler   +8 more
wiley   +1 more source

(E)-N’-(1-(Benzofuran-2-yl)ethylidene)-1-(4-Methoxyphenyl)-5-Methyl-1H-1,2,3-Triazole-4-Carbohydrazide

open access: yesMolbank, 2023
The reaction of equimolar equivalents of 1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbohydrazide (1) and 2-acetylbenzofuran (2) in anhydrous ethanol containing a catalytic amount of concentrated hydrochloric acid under reflux for 2 h gave (E)-N’-(
Bakr F. Abdel-Wahab   +3 more
doaj   +1 more source

Acidogenesis‐Propelled Coordination Transition in Light‐Triggered Fe‐Polyphenol Polymer for Reactive Oxygen Species‐Augmented Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A novel iron‐polyphenol‐photoacid coordination polymer (FeBPs) is designed to achieve red light‐triggered external acidification and internal coordination regulation, where this light‐controlled acidification induces coordination changes that enhance Fe active site exposure and provide H+ for beneficial Fe3+/Fe2+ conversion, thereby accelerating ROS ...
Ying Wan   +7 more
wiley   +1 more source

Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine.

open access: yesPLoS ONE, 2013
Triazoles are known for their non-toxicity, higher stability and therapeutic activity. Few nucleoside (L1, L2 and L3) and non-nucleoside 1,2,3-triazoles (L4-L14) were synthesised using click chemistry and they were screened for tumor cell cytotoxicity ...
Jerald Mahesh Kumar   +10 more
doaj   +1 more source

Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles [PDF]

open access: yesMedChemComm, 2017
A series of prenyl 1,2,3-triazoles were prepared from isoprenyl azides and different alkynes. Most of the compounds were active against T. cruzi and L. donovani.
Guillermo R. Labadie   +7 more
openaire   +4 more sources

Antimicrobial studies of unsymmetrical bis-1,2,3-triazoles [PDF]

open access: yesOrganic and Medicinal Chemistry Letters, 2012
Aryl azides were treated with allenylmagnesium bromide to generate 1,5-disubstituted butynyl 1,2,3-triazoles in a domino fashion, which upon Cu(I) catalyzed 1,3-dipolar cycloaddition with aryl azides afforded novel bis-1,2,3-triazoles in quantitative yields.
Bashir A. Ganai   +2 more
openaire   +3 more sources

Stimuli‐Responsive Supramolecular Polymers of Mono‐ and Bis‐triazolylphenylazoaniline‐Functionalized Copillar[5]Arenes: With Distinctive Binding Modes

open access: yesChemistry – An Asian Journal, EarlyView.
Mono‐ and bis‐functionalized copillar[5]arenes 1 and 2 form pH‐ and photo‐responsive supramolecular polymers. Protonation of 1 enhances polymerization (1‐H), differing from neutral 2, which forms a 1:1 complex with DMP5 via cavity binding. Polymerization and morphology are tunable by pH and light, as shown by NMR, UV–vis, and FE‐SEM analyses.
Chun‐Yi Yao   +6 more
wiley   +1 more source

Biological importance and synthesis of 1,2,3-triazole derivatives: a review

open access: yesGreen Chemistry Letters and Reviews
1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential ...
Mira J. Vaishnani   +8 more
doaj   +1 more source

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