Results 101 to 110 of about 2,669,160 (149)

27-hydroxycholesterol and DNA damage repair: implication in prostate cancer. [PDF]

Front Oncol, 2023
Galvan GC, Friedrich NA, Das S, Daniels JP, Pollan S, Dambal S, Suzuki R, Sanders SE, You S, Tanaka H, Lee YJ, Yuan W, de Bono JS, Vasilevskaya I, Knudsen KE, Freeman MR, Freedland SJ.   +16 more
europepmc   +1 more source

Survival signals induced by low concentrations of 27-hydroxycholesterol in human monocytic cells via ERK activation

, 2012
Oxysterols are oxidized derivatives of cholesterol, most likely contributing to the development of atherosclerosis. On the basis of the clear findings by previous workers about oxysterol-mediated induction of survival pathways aside that of death ...
Vuruşaner Aktaş, Beyza, Poli, Giuseppe, Başağa, Hüveyda   +2 more
core   +1 more source

The Cytotoxicity of 27-Hydroxycholesterol in MCF-7 and MDA-MB-231. [PDF]

Adv Biomed Res, 2023
Rashidi Alavijeh M, Etesami H, Dehghan A, Babajani A, Haghjooy Javanmard S.   +4 more
europepmc   +1 more source

27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation

, 2017
Hypercholesterolemia is associated with cognitively deteriorated states. Here, we show that excess 27-hydroxycholesterol (27-OH), a cholesterol metabolite passing from the circulation into the brain, reduced in vivo brain glucose uptake, GLUT4 expression,
Laura Mateos, Zeina Ali, Irina Savitcheva, Eric Westman, Muhammad-Al-Mustafa Ismail, Paula Merino-Serrais, Angel Cedazo-Mínguez, Maria Lodeiro, Eran Leitersdorf, Ingemar Björkhem, Balázs Gulyás, Lars Olof-Wahlund, Silvia Maioli, Bengt Winblad   +13 more
core   +1 more source

27-Hydroxycholesterol represses G9a expression via oestrogen receptor alpha in breast cancer. [PDF]

J Cell Mol Med, 2023
Vini R, Lekshmi A, Ravindran S, Thulaseedharan JV, Sujathan K, Rajavelu A, Sreeja S.   +6 more
europepmc   +1 more source

Deciphering the role of 27-hydroxycholesterol in neurodegeneration

, 2016
Cholesterol is constantly attributed to neurodegenerative diseases including Alzheimer’s disease (AD). This is due to the association of high blood cholesterol and the consequences of cholesterol metabolism in these conditions. However the brain isolates
Muhammad Ismail (18637081)
core   +1 more source

27-Hydroxycholesterol promotes metastasis by SULT2A1-dependent alteration in hepatocellular carcinoma. [PDF]

Cancer Sci, 2022
He T, Tao B, Yi C, Zhang C, Zhang P, Shao W, Li Y, Chen Z, Lu L, Jia H, Zhu W, Lin J, Chen J.   +12 more
europepmc   +1 more source

Circulating 27-hydroxycholesterol, lipids, and steroid hormones in breast cancer risk: a nested case-control study of the Multiethnic Cohort Study. [PDF]

Breast Cancer Res, 2023
DeRouen MC, Yang J, Li Y, Franke AA, Tome AN, White KK, Hernandez BY, Shvetsov Y, Setiawan V, Wu AH, Wilkens LR, Le Marchand L, Loo LWM, Cheng I.   +13 more
europepmc   +1 more source

A novel sex-specific role for 27-hydroxycholesterol in early-onset schizophrenia. [PDF]

Ann Gen Psychiatry
Sun Z, Liu M, Yan J, Wu Y, Wang H, Li Y, Tang Y, Zheng Y, Li R.   +8 more
europepmc   +1 more source

27-hydroxycholesterol causes cognitive deficits by disturbing Th17/Treg balance and the related immune responses in mild cognitive impairment patients and C57BL/6J mice. [PDF]

J Neuroinflammation, 2023
Wang T, Feng W, Ju M, Yu H, Guo Z, Sun X, Yang K, Liu M, Xiao R.   +8 more
europepmc   +1 more source