Results 131 to 140 of about 26,813 (237)

Impact of the ABCB1 Drug Resistance Gene on the Risk Factors of Patients with COVID-19 and Its Relationship with the Drugs Used

Infection and Drug Resistance, 2022
Irma Olarte Carrillo,1 Christian Omar Ramos Peñafiel,2 Iveth Mendoza Salas,2 Rafael Cerón Maldonado,1 Anel Irais García Laguna,1 Adrián De la Cruz Rosas,1 Carlos Martinez Murrillo,2 Adolfo Martinez Tovar1 1Laboratorio de Biología Molecular, Servicio de ...
Olarte Carrillo I, Ramos Peñafiel CO, Mendoza Salas I, Cerón Maldonado R, García Laguna AI, De la Cruz Rosas A, Martinez Murrillo C, Martinez Tovar A   +7 more
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Association Between ABCB1 Gene Polymorphism with Hyperglycemia and MACE in Patients Undergoing Clopidogrel Treatment After PCI

Bo Zhou,1,* Chuanshen Shi,2,* Qike Xu,1 Yujia Wei,3 ShuFang Zhang,1 Xia Wang,1 Xiangyang An1 1Clinical Pharmacy, The Affiliated Taian City Central Hospital of Qingdao University, Taian, Shandong, People’s Republic of China; 2Clinical ...
Shi C, Zhou B, Xu Q, An X, Wang X, Zhang S, Wei Y   +6 more
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The impact of ABCB1 (rs1045642 and rs4148738) and CES1 (rs2244613) gene polymorphisms on dabigatran equilibrium peak concentration in patients after total knee arthroplasty

, 2018
Dmitriy Alekseevich Sychev,1 Alexander Nikolaevich Levanov,2 Tatiana Vladimirovna Shelekhova,2 Pavel Olegovich Bochkov,3 Natalia Pavlovna Denisenko,4 Kristina Anatolyevna Ryzhikova,4 Karin Badavievich Mirzaev,3 Elena Anatolyevna Grishina,4 Mikhail ...
Ramenskaya GV, Ryzhikova KA, Sychev DA, Levanov AN, Shelekhova TV, Grishina EA, Gavrilov MA, Mirzaev KB, Denisenko NP, Kozlov AV, Bogoslovsky T, Bochkov PO   +11 more
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Exploring bat-inspired cyclic tryptophan diketopiperazines as ABCB1 Inhibitors

Communications Chemistry
Chemotherapy-induced drug resistance remains a major cause of cancer recurrence and patient mortality. ATP binding cassette subfamily B member 1 (ABCB1) transporter overexpression in tumors contributes to resistance, yet current ABCB1 inhibitors have ...
Javier Yu Peng Koh, Yoko Itahana, Alexander Krah, Habib Mostafa, Mingmin Ong, Sahana Iwamura, Dona Mariya Vincent, Sabhashina Radha Krishnan, Weiying Ye, Pierre Wing Chi Yim, Tushar M. Khopade, Kunihiko Chen, Pui San Kong, Lin-Fa Wang, Roderick W. Bates, Yasuhisa Kimura, Rajesh Viswanathan, Peter J. Bond, Koji Itahana   +18 more
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ABCB1 is critical for SALL4-induced drug resistance.

, 2015
(A) Western blotting showed that ectopic overexpression of SALL4 upregulated ABCB1 protein expression in Ishikawa cells and knockdown of SALL4 in AN3CA cells downregulated ABCB1 expression.
Huali Xu (800184), Xiaoming Yang (113295), Xiaowei Xi (579191), Jing Zhang (23775), Chi Fang (800183), Lei Liu (5074)   +5 more
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Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients?

, 2017
Eric Rytkin,1 Karin B Mirzaev,1 Elena A Grishina,1 Valeriy V Smirnov,2 Kristina A Ryzhikova,1 Zhannet A Sozaeva,1 Michael Iu Giliarov,2 Denis A Andreev,2 Dmitriy A Sychev1 1Russian Medical Academy of Continuous Professional Education, 2I.M.
Rytkin E, Smirnov VV, Ryzhikova KA, Sychev DA, Sozaeva ZA, Grishina EA, Andreev DA, Mirzaev KB, Giliarov MI   +8 more
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Effect of ABCB1 SNP polymorphisms on the plasma concentrations and clinical outcomes of rivaroxaban in Chinese NVAF patients: a population pharmacokinetic-based study

Frontiers in Pharmacology
BackgroundThis study utilized a population pharmacokinetic (PPK) approach to assess the influence of ABCB1 genetic polymorphisms on the plasma concentrations and clinical outcomes of rivaroxaban.MethodsThe PPK model for rivaroxaban was developed using ...
Fei Wang, Ze Li, Youqi Huang, Qin Liu, Libin Zhao, Honghong Wang, Honghong Wang, Hongjin Gao, Mingyu Chen, Yuze Lin, Xingang Li, Min Chen   +11 more
doaj   +1 more source

The role of ABCB1 transporter gene in breast cancer resistance.

, 2009
Abstract #4158 Background: Cellular multidrug resistance (MDR) to anticancer drugs remains one of the primary causes of suboptimal outcomes in cancer therapy.
V Pecha, M Mrhalova, P Soucek, I Gut, GA Alnaes, R Vaclavikova, M Hubackova, I Hlavata, VN Kristensen, SH Nordgard, R Kodet   +10 more
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Pharmacogenetics of Efavirenz response in Bantu-speaking South African HIV/AIDS patients

, 2011
Includes abstract.Includes bibliographical references (leaves 82-96).Efavirenz (EFV) is used in first-line antiretroviral (ARV) therapy of HIV-infected patients, and is principally metabolised by CYP1A2, CYP2A6, CYP2B6, CYP3A4/5 and the drug transporter ...
Swart, Marelize
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ABCB1 gene polymorphisms and violent suicide attempt among survivors

, 2015
International audienceINTRODUCTION:Those suicide attempters that choose violent methods dramatically diminish the possibility of survival. Completed suicide using violent means, which is common among first-time suicide attempters, was recently found to ...
Llerena, A., Delgado, A., Naranjo, M.E., Guillaume, S., Peñas-Lledó, E., Jaussent, I., Courtet, P.   +6 more
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