Development and validation of a novel diagnostic test for human brucellosis using a glyco-engineered antigen coupled to magnetic beads. [PDF]
PLoS Neglected Tropical Diseases, 2013 Brucellosis is a highly contagious zoonosis and still a major human health problem in endemic areas of the world. Although several diagnostic tools are available, most of them are difficult to implement especially in developing countries where complex ...
Andrés E Ciocchini +8 more
doaj +6 more sources
Development of a set of bacterial engineered glycoconjugates as novel serogroup-specific antigens for the serodiagnosis of Escherichia coli O26, O111, O103 and O45 infections associated to hemolytic uremic syndrome [PDF]
Microbial Cell FactoriesHemolytic uremic syndrome associated to Shiga toxin-producing Escherichia coli infection (STEC-HUS) is a life-threatening condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney failure. Among STEC, E.
Ana J. Caillava +9 more
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AcrAB Efflux Pump Plays a Crucial Role in Bile Salts Resistance and Pathogenesis of Klebsiella pneumoniae [PDF]
AntibioticsBile salts possess innate antibacterial properties and can cause significant damage to bacteria. To survive in the mammalian gut, Klebsiella pneumoniae has developed mechanisms to tolerate bile salts; however, the specific mechanisms remain unclear ...
Rundong Shu +5 more
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Circulation: Cardiovascular Interventions, 2019 BACKGROUND: Transradial intervention (TRI) may impair digital perfusion with hand dysfunction as a result. However, the effect of TRI on digital perfusion has never been investigated, including the influence of variations of the collateral arterial network and the effect on hand dysfunction.
Leeuwen, M.A.H. van +8 more
openaire +5 more sources
Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein
Nature Communications, 2023 Membrane efflux pumps play a major role in bacterial multidrug resistance. The tripartite multidrug efflux pump system from Escherichia coli, AcrAB-TolC, is a target for inhibition to lessen resistance development and restore antibiotic efficacy, with ...
Benjamin Russell Lewis +11 more
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Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators
Biomolecules, 2023 Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium.
Tania Szal +8 more
doaj +1 more source
Regular Combinators for String Transformations [PDF]
, 2014 We focus on (partial) functions that map input strings to a monoid such as the set of integers with addition and the set of output strings with concatenation.
Alur R. +3 more
core +2 more sources
Expression of the Fluoroquinolones Efflux Pump Genes acrA and mdfA in Urinary Escherichia coli Isolates [PDF]
Polish Journal of Microbiology, 2017 Escherichia coli is one of the most frequent causes of urinary tract infections. Efflux system overexpression is reported to contribute to E. coli resistance to several antibiotics. Our aim in this study was to investigate the relation between antibiotic
Sarah M. Abdelhamid, Rania R. Abozahra
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A bacterial glycoengineered antigen for improved serodiagnosis of porcine brucellosis [PDF]
, 2016 Brucellosis is a highly zoonotic disease that affects animals and human beings. Brucella suis is the etiological agent of porcine brucellosis and one of the major human brucellosis pathogens.
Balzano, Rodrigo E. +9 more
core +1 more source
Корпоративные финансы, 2017 This research addresses the problem of pension savings and pension reserves management efficiency analysis of the whole Russian pension system and non-state pension funds.
Yury Nogin
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